课题基金 / 基金详情

SIGNAL TRANSDUCTION AND MOTILITY IN TUMOR CELL MIGRATION

SIGNAL TRANSDUCTION AND MOTILITY IN TUMOR CELL MIGRATION
肿瘤细胞迁移中的信号转导和运动
批准号：
6475919
负责人：
CHENG DONG
金额：
$10.07万
依托单位：
PENNSYLVANIA STATE UNIVERSITY, THE
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-15 至 2003-11-30
来源：
https://reporter.nih.gov/project-details/6475919
关键词：
biological signal transduction calcium flux calcium ion cell line cell migration cell motility cellular oncology cytoskeleton extracellular matrix lipids mathematical model melanoma metastasis single cell analysis stainings

项目摘要

项目成果

CHENG DONG的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
The aims are: (1) to characterize the role of lipids in signal transduction by ECM molecules for tumor cell pseudopod protrusion and migration; (2) to determine the response of intracellular calcium cations in tumor cells to lipid-mediated ECM molecule stimulation; (3) to examine the response of the cytoskeletal actin network upon lipid- mediated ECM molecule stimulation during the two phase pseudopod protrusion; and (4) to construct a two phase pseudopod model integrating engineering sciences with cell biology and derive mechanistic parameters that may affect tumor cell migration.
期刊论文(5)
专著(0)
科研奖励(0)
会议论文
Application of the dual-micropipet technique to the measurement of tumor cell locomotion.
双微移液器技术在肿瘤细胞运动测量中的应用。
DOI： 10.1006/excr.1999.4388
发表时间： 1999
期刊： Experimental cell research.
影响因子： --
作者： [You,J, Mastro,AM, Dong,C]
通讯作者： Dong,C
BMES-SPRBM Conference on Cellular and Molecular Bioengineering
STUDY OF MOLECULAR DYNAMICS IN LEUKOCYTE-ASSISTED MELANOMA EXTRAVASATION
Multiscale modeling of leukocyte-tumor cell adhesion to endothelium in shear flow
STUDY OF MOLECULAR DYNAMICS IN LEUKOCYTE-ASSISTED MELANOMA EXTRAVASATION
海外基金