Stabilisation of cold-adapted lipases and their consumer-product applications

该项目将涉及从极端细菌和古细菌中识别具有改进性能的新型酶，用于洗涤剂和医疗保健部门。具体地说，从有利于可持续冷水洗涤的嗜冷生物中分离出的酶将是优先考虑的。将开发一种改进的超量表达平台，用于高产嗜冷酶。最优先的酶将从生化和结构两个方面进行表征，从而允许采用合理的方法来提高稳定性。

The project will be involved in identifying novel enzymes from extremophilic bacteria and archaea that have improved properties for use in the detergent and healthcare sector. Specifically enzymes isolated from psychrophilic organisms that are favoured for sustainable cold water washing will be a priority. An improved over-expression platform for psychrophilic enzymes at high yield will be developed. The highest priority enzymes will be characterised both biochemically and structurally allowing a rational approach for improved stability.