Stabilisation of cold-adapted lipases and their consumer-product applications

冷适应脂肪酶的稳定性及其消费品应用

• 批准号: 2094129
• 金额: --
• 依托单位: UNIVERSITY OF EXETER
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2094129
• 关键词: Stabilisation; cold; adapted; lipases; their

The project will be involved in identifying novel enzymes from extremophilic bacteria and archaea that have improved properties for use in the detergent and healthcare sector. Specifically enzymes isolated from psychrophilic organisms that are favoured for sustainable cold water washing will be a priority. An improved over-expression platform for psychrophilic enzymes at high yield will be developed. The highest priority enzymes will be characterised both biochemically and structurally allowing a rational approach for improved stability.

该项目将参与从嗜极端细菌和古细菌中鉴定新型酶，这些酶具有改进的特性，可用于洗涤剂和医疗保健领域。特别是从嗜冷生物中分离出来的酶，有利于可持续的冷水洗涤，这将是一个优先事项。将开发一种改进的高产量嗜冷酶过表达平台。最高优先级的酶将在生物化学和结构上进行表征，从而允许合理的方法来改善稳定性。