FASEB Summer Research Conference on Small G-Proteins

FASEB 小 G 蛋白夏季研究会议

• 批准号: 6507117
• 负责人: Linda Van Aelst
• 金额: $ 1万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2003-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6507117
• 关键词: G protein; guanine nucleotide binding protein; guanosinetriphosphatases; meeting /conference /symposium; protein structure function; travel

DESCRIPTION (provided by applicant): The Federation of American Societies for Experimental biology (FASEB) Conference on the Ras Superfamily of GTPases will be held from July 6-11, 2002 at Snowmass Village, Colorado. This will be the sixth such conference, and it has been authorized by FASEB because of the success of the previous conferences. This application seeks partial support for the operation of this conference. The focus of the conference will be on the function, regulation and structure of five main branches of Ras-related GTPases: Ras, Rho, Rab, Arf and Ran. In particular, special emphasis will be given to the function of these GTPases in physiological processes and their interconnections. Also, the present trend of post-genomics, and novel techniques for live cell imaging will be highlighted. Research on the above GTPases is proceeding at a rapid pace, revealing the fundamental importance in the signal transduction pathways that govern fundamental aspects of cell growth, adhesion, differentiation and development. Aberrations in signaling pathways mediated by several of these G proteins have been associated with different disease phenotypes, including tumor formation, metastasis, and cognitive diseases. Within the past few years, numerous regulators and effectors have been isolated for these GTPases and crystal structures of several G proteins, their regulators and effectors have now been determined yielding important insights into their mechanisms of regulation. This conference will serve as a forum for dissemination of the most recent information of the function, structure and regulation of the GTPases, their regulators and effectors. Like other FASEB Summer Conferences, this meeting selected approximately 200 participants from applications, including representatives from industry and academia. There is a constant infusion of new researchers from various disciplines and the 2002 conference will be important for a focused presentation and discussion of the genetics, biochemistry and cell biology of the small GTPases, their regulations and effectors. The conference will consist of nine sessions, each with a discussion leader and at least five speakers, selected from investigators who have made important recent contributions and from submitted abstracts. In addition, there will be at least ten short talks selected from submitted abstracts. This will help to ensure inclusion of young investigators, women and minorities as primary participants. Also, three poster sessions will be organized which will provide another important format for scientific exchange.

描述（由申请人提供）： 美国GTPases RAS超家族的实验生物学联合会（FASEB）会议将于2002年7月6日至11日在科罗拉多州的雪地村举行。 这将是第六次这样的会议，由于先前的会议的成功，因此已由FaseB授权。 该应用程序为本次会议的运作寻求部分支持。 会议的重点将放在与RAS相关的GTPases的五个主要分支的功能，调节和结构上：RAS，RHO，RAB，ARF和RAN。 特别是，将特别强调这些GTPases在生理过程及其互连中的功能。 此外，将突出显示后基因组学的当前趋势以及实时细胞成像的新技术。 对上述GTPASE的研究正在以快速的速度进行，揭示了控制细胞生长，粘附，分化和发育基本方面的信号转导途径的基本重要性。 这些G蛋白中的几种介导的信号通路的畸变与不同的疾病表型有关，包括肿瘤形成，转移和认知疾病。 在过去的几年中，已经为这些GTPase和几种G蛋白的晶体结构分离了许多调节剂和效应子，现在已经确定了它们的调节剂和效应子，从而对其调节机制产生了重要的见解。 这次会议将作为传播GTPases功能，结构和调节的最新信息，其监管机构和效应子的最新信息的论坛。 与其他FASEB夏季会议一样，这次会议选择了来自申请的大约200名参与者，包括工业和学术界的代表。 来自各个学科的新研究人员不断注入，2002年会议将对小型GTPases的遗传学，生物化学和细胞生物学的重点介绍和讨论非常重要。 该会议将包括九个会议，每个会议都有一个讨论的领导者和至少五位发言人，这些调查员是从研究人员做出了重要贡献和提交摘要的调查人员中选出的。 此外，将至少从提交的摘要中选择十个简短的会谈。 这将有助于确保将年轻的调查人员，妇女和少数民族作为主要参与者。 此外，将组织三个海报会议，这将为科学交流提供另一种重要格式。