Gordon Conference: Second Messengers and Phosphorylation

描述（由申请人提供）：我请求部分支持戈登研究会议（GRC）第二信使和蛋白质磷酸化会议的运作。这个GRC通常在新罕布什尔州梅里丁的金博尔联盟学院举行，它提供了一个熟悉的场所，以促进参与者之间的开放互动。本次GRC于2002年6月9日星期日晚上开始，由一位全体发言人发言，并于6月13日星期四晚上结束。会议的重点是蛋白激酶信号转导机制，调节细胞的生长，生存和代谢。对这些信号机制的充分理解在科学和临床上都很重要，因为它们的失败在影响全球数百万人的当代健康问题中起着直接作用。鼓励演讲者整合生物化学，结构，细胞生物学和基因组学方法，以提供对信号传导机制分子方面的全面理解。全体演讲者将被选中为会议搭建舞台，并挑战与会者从新颖的角度思考信号转导。会议将包括8场会议，每场会议有一名讨论负责人和至少四名发言人，发言人从最近做出重要贡献的调查人员中选出;至少20%的发言人是妇女或成员或少数群体。每个环节的演讲者将开发信号转导重要范例的结构和功能，并将这些系统与疾病机制和潜在的治疗策略联系起来。我将从申请者中选出135名参与者，包括来自工业界和学术界的代表，资深科学家，博士后研究员和研究生。鼓励参加者每天下午展示新的和有趣的结果。重要的是，会议为年轻的研究人员提供了一个论坛，让他们看到基础科学研究与科学方法应用于设计人类疾病有效干预措施之间的联系，包括癌症，糖尿病，肥胖，衰老和神经退行性疾病。为了强调这一目标，将挑选四个与会议主题相辅相成的海报介绍，在主要会议期间作简短的口头介绍。

DESCRIPTION (provided by applicant): I am requesting partial support for the operation of the Gordon Research Conference (GRC) Conference on Second Messengers and Protein Phosphorylation. This GRC is usually held at Kimball Union Academy in Meridin, New Hampshire, which provides a familiar venue to promote open interaction among participants. This GRC begins on Sunday night June 9, 2002 with a plenary speaker and concludes on Thursday evening June 13. The Conference focuses on protein kinase signal transduction mechanisms that regulate cellular growth, survival and metabolism. A full understanding of these signaling mechanisms is scientifically and clinically important because their failure plays a direct role in contemporary health problems that affect millions of people worldwide. The speakers are encouraged to integrate biochemical, structural, cell biological and genomic approaches into providing a comprehensive understanding of the molecular aspects of signaling mechanisms. The plenary speaker will be selected to set the stage for the conference and challenge the participants to think about signal transduction from a novel perspective. The conference will consist of 8 sessions, each with a discussion leader and at least four speakers, selected from investigators who have made important recent contributions; at least 20% of the speakers are women or members or minorities groups. Speakers in each session will develop the structure and function of important paradigms in signal transduction and relate these systems to disease mechanisms and potential treatment strategies. I will select 135 participants from applicants, including representatives from industry and academia, senior scientists, postdoctoral fellows and graduate students. Participants are encouraged to present poster on new and interesting results each afternoon. Importantly, the conference provides a forum for young investigators to see the connection between fundamental scientific inquiry and the application of scientific methods to the design of efficacious interventions for human diseases, including cancer, diabetes, obesity, aging and neurodegeneration. To emphasize this goal, four poster presentations that complement the theme of the meeting will be selected for brief oral presentations during the major sessions.