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Conference: Molecular Mechanism of Leukocyte Trafficking

Conference: Molecular Mechanism of Leukocyte Trafficking
会议:白细胞贩运的分子机制
批准号:
6457174
负责人:
STEVEN D ROSEN
金额:
$0.25万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-05-15 至 2003-04-30

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中文摘要
翻译
描述(由申请人提供):关于“分子生物学”的Keystone会议 白细胞运输的机制”将是一个全面的聚会, 世界上最重要的科学家在一个前沿的基础科学领域工作, 对人类疾病的重要影响。 这次会议是一次 非常成功的联席会议 关于“白细胞的分子机制 1998年3月举行了“贩运”和“内皮素”研讨会。 过去几年 看到了对白细胞如何外渗的理解的不断进步, 迁移 在组织内。 一直 得到进一步阐明 的 选择素及其配体;趋化因子及其受体; 整联蛋白;和IG超家族分子。 一些新的战略, 抗炎治疗已经从这些学科中出现, 更多的人可能会效仿。这次会议将汇集科学家, 在白细胞和血管生物学的各种主题。所得 相互作用可能会刺激新的方法来解决关键的剩余问题, 贩运研究的问题。
英文摘要
DESCRIPTION (provided by applicant): The Keystone meeting on "Molecular Mechanisms of Leukocyte Trafficking" will be a comprehensive gathering of the world's foremost scientists working in a cutting-edge basic science area with important ramifications for human disease. This meeting is a reprise of a highly successful joint meeting on "Molecular Mechanisms of Leukocyte Trafficking" and "Endothelium" held in March 1998. The past few years have seen continued advances in the understanding of how leukocytes extravasate and migrate within tissues. There has been further elucidation of the participation of: selectins and their ligands; chemokines and their receptors; integrins; and Ig superfamily molecules. A number of novel strategies for anti-inflammatory therapeutic have already emerged from these disciplines and more are likely to follow. The meeting will bring together scientists working in diverse range of topics in leukocyte and vascular biology. The resulting interactions are likely to stimulate new approaches to the critical remaining problems in trafficking research.
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