TERRY BEIRN COMMUNITY PROGRAMS FOR CLINICAL RESEARCH ON

特里·拜恩 (Terry BEIRN) 临床研究社区计划

• 批准号: 6510768
• 负责人: James Dennis Neaton
• 金额: $ 425.6万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-05-01 至 2005-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6510768
• 关键词: AIDS; biomedical facility; clinical research; clinical trials; cooperative study; data collection; data management; experimental designs; human data; statistics /biometry

The Community Programs for Clinical Research on AIDS (CPCRA) is a community-based clinical trials group which proposes to include 19 units in the United States and clinical sites in Australia, Canada, and the United Kingdom. This is a proposal for the Statistical and Data Management Center (SDMC) for this trials group. The SDMC bears primary responsibility for the statistical components of the science agenda outlined in the accompanying core proposal. The SDMC also has primary responsibility for the development of data collection, management, and reporting procedures that ensure that the studies are properly implemented and monitored. Objectives fall into four broad and interrelated areas: l) to provide statistical leadership to the group by collaborating on the development of an integrated scientific agenda, by using innovative approaches in the design of studies, by carrying out interim and final analyses, and by conducting seminars on research methods; 2) to continue to enhance systems for collecting, processing and reporting data in a timely and efficient way so that study objectives are met; 3) to collaborate with national trial coordinating centers in Australia, Canada, and the United Kingdom which will assist with randomization procedures, data management, and data analysis, and to collaborate with other clinical trial groups on specific studies; and 4) to work closely with all of the organizational groups and committees in the CPCRA to carry out the scientific agenda, and to maintain a SDMC organizational structure and staff that aligns with the larger CPCRA organization and provides a stimulating work atmosphere and peer support.

社区艾滋病临床研究计划（CPCRA）是一个以社区为基础的临床试验组织，计划在美国建立19个单位，在澳大利亚、加拿大和英国建立临床研究中心。这是针对本试验组的统计和数据管理中心（SDMC）的提案。 SDMC对所附核心提案中概述的科学议程的统计部分负有主要责任。SDMC还主要负责制定数据收集、管理和报告程序，以确保研究得到适当实施和监测。目标分为四个广泛和相互关联的领域：l）通过合作制定综合科学议程、在研究设计中采用创新方法、进行中期和最后分析以及举办研究方法研讨会，向该小组提供统计领导; 2）继续加强及时有效地收集、处理和报告数据的系统，以实现研究目标; 3）与澳大利亚、加拿大和英国的国家试验协调中心合作，协助进行随机化程序、数据管理和数据分析，并与其他临床试验小组合作进行特定研究; 4）与CPCRA的所有组织小组和委员会密切合作，以执行科学议程，并保持SDMC的组织结构和工作人员与更大的CPCRA组织保持一致，并提供激励工作氛围和同行支持。