VERMONT BREAST CANCER SURVEILLANCE SYSTEM

佛蒙特州乳腺癌监测系统(BVCS)建议继续加入乳腺癌监测联盟(BCSC)。作为美国最农村的州，佛蒙特州非常适合补充目前在NCI联盟中代表的更多城市地点。我们的目标是让我们的佛蒙特州多学科研究团队与其他BCSC站点的其他研究人员和NCI工作人员一起进行协作的乳腺癌监测研究。我们核心建议的目标是：a)维持和改进全面的、质量受控的全州监测系统，该系统可以访问现有的记录，并从乳房X光检查设施、病理实验室和基于人群的癌症登记中收集新的信息；b)继续和扩大佛蒙特州和NCI乳腺癌监测联盟的基础科学研究人员、临床研究人员和应用研究人员之间的乳腺癌研究合作与互动；c)通过开展系统研究来检查乳腺癌筛查和诊断的可操作性，以评估筛查计划和诊断技术在提高分期诊断和乳腺癌死亡率方面的有效性和效率。这两个特别研究项目的重点是使用标准的四视图筛查乳房X光检查之外的额外成像。在项目1中，我们将确定使用额外的乳房X光检查和/或超声与标准的四视图乳房X光检查相比的诊断准确性。在项目2中，我们将确定被召回进行额外成像的心理、社会和行为影响。

The Vermont Breast Cancer Surveillance System (BVCSS) proposes to continue membership in the Breast Cancer Surveillance Consortium (BCSC). As the most rural state in the nation, Vermont is well suited to complement more urban sites currently represented in the NCI Consortium. Our goal is to have our Vermont multi- disciplinary team of researchers join with other investigators at other BCSC sites and the NCI staff to conduct collaborative breast cancer surveillance research. Our aims for the core proposal are: a) to maintain and improve a comprehensive, quality controlled, statewide surveillance system that accesses existing records and collects new information from mammography facilities, pathology laboratories, and a population-based cancer registry; b) to continue and expand breast cancer research collaborations and interactions among basic science researchers, clinical researchers and applied researchers in Vermont and in the NCI Breast Cancer Surveillance Consortium; c) to examine the operational aspects of breast cancer screening and diagnosis by conducting systematic research designed to assess the effectiveness and efficiency of screening programs and diagnostic techniques as they relate to the improvement of stage at diagnosis and breast cancer mortality. The two special research projects are focused on the use of additional imaging beyond the standard four-view screening mammogram. In project 1 we will determine the diagnostic accuracy of using either additional mammographic views and/or ultrasound compared with the standard four-view mammogram. In project 2 we will establish the psychological, social and behavioral effects of being recalled for additional imaging.