CORE--BIOSTATISTICS FACILITY

核心——生物统计设施

• 批准号: 6658306
• 负责人: SYLVAN B. GREEN
• 金额: $ 7.89万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-13 至 2003-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6658306
• 关键词: animal data; biomedical facility; human data; statistics /biometry

DESCRIPTION (provided by applicant): The Biostatistics Core Facility brings together expertise and intellectual resources in biostatistics, clinical trials, epidemiology, statistical computing, and database and information management. The Core Facility has wide involvement in support of Cancer Center research in clinical trials, prevention and cancer control research, genetic and population studies, and translational research. Activities include: 1) protocol development; 2) protocol review; 3) study monitoring; 4) data analysis and reporting; 5) database development and management; 6) applications with large population databases; 7) data services and computer programming; 8) research-related website development; 9) education; and 10) statistical consultation and collaboration. The Core Facility closely supports activities of the Clinical Trials Unit. Biostatisticians are actively involved in review of all protocols as part of the Clinical Trials Development and Review Committee. Recent recruitment of the Core Facility has enhanced the biostatistical support of Cancer Center activities, allowing the fostering of the philosophy that productive research requires high quality biostatistical collaboration. Activities of the Core Facility in support of cancer research are illustrated by work on clinical trial protocol development in developmental therapeutics, data mining (genetic microarray data), genetic epidemiology (such as the Colon Polyp and Colon Cancer Sib Pair Study), behavioral research, development of an interactive Clinical Trials Database, and exploration of large population databases for research on cancer preventive and treatment service delivery. The Core Facility has supported research in each of the Programs in the Cancer Center. Collaboration of Core Facility personnel with Cancer Center investigators on the design, operation, analysis, and interpretation of cancer studies has enhanced the quality of the science.

描述（由申请人提供）：生物统计学核心机构带来了 将生物统计学、临床医学、 试验、流行病学、统计计算、数据库和信息 管理核心基金广泛参与支持癌症 临床试验、预防和癌症控制研究中心， 遗传和人口研究，以及转化研究。活动 包括：1）方案制定; 2）方案审查; 3）研究监查; 4） 数据分析和报告; 5）数据库开发和管理; 6） 大型人口数据库的应用; 7）数据服务和计算机 编程; 8）与研究相关的网站开发; 9）教育;以及10） 统计咨询和协作。核心设施紧密 支持临床试验部门的活动。生物统计学家 作为临床试验的一部分，积极参与所有方案的审查 发展和审查委员会。核心基金最近的征聘工作 加强了对癌症中心活动的生物统计支持， 培养生产性研究需要高质量的理念 生物统计合作。核心基金为支持 癌症研究通过临床试验方案的制定得到说明 在发育治疗学，数据挖掘（基因微阵列数据），遗传 流行病学（例如结肠息肉和结肠癌同胞对研究）， 行为研究，开发交互式临床试验数据库， 和探索用于癌症研究的大型人口数据库 提供预防和治疗服务。核心基金支持 在癌症中心的每个项目中进行研究。核心合作 设施人员与癌症中心研究人员就设计、操作、 癌症研究的分析和解释提高了 科学