PREVENTION OF K AND MG DEPLETION BY KMAG CITRATE

通过 KMAG 柠檬酸盐预防 K 和 MG 消耗

• 批准号: 6567652
• 负责人: CHARLES Y.C PAK
• 金额: $ 32.14万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-12-01 至 2002-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6567652
• 关键词: alcoholism /alcohol abuse chemotherapy; citrates; clinical research; disease /disorder prevention /control; human subject; magnesium deficiency; magnesium ion; pharmacokinetics; potassium deficiency; potassium ion

The overall goal of this study is to assess the value of potassium- magnesium citrate in preventing hypokalemia and magnesium depletion in patients taking diuretics. The hypothesis to be tested is that K-Mag citrate is capable of meeting these objectives because of its high bioavailability. When the above goal is met, an ancillary goal will be to examine the effect of K-Mag citrate in magnesium depletion of non- diuretic use (chronic alcoholism).

这项研究的总体目标是评估钾的价值- 柠檬酸镁预防低钾血症和镁耗竭 服用利尿剂的患者。 要检验的假设是， 柠檬酸盐能够满足这些目标，因为它的高 生物利用度 当上述目标实现时，将有一个辅助目标。 检查K-Mag柠檬酸盐在非- 使用利尿剂（慢性酒精中毒）。