COMPREHENSIVE EVALUATION OF OSTEOPOROSIS

骨质疏松症的综合评估

• 批准号: 6567637
• 负责人: CHARLES Y.C PAK
• 金额: $ 32.14万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-12-01 至 2002-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6567637
• 关键词: adrenal glands; alkaline phosphatase; bone density; bone metabolism; clinical research; diagnosis design /evaluation; disease /disorder classification; disease /disorder proneness /risk; human subject; hydroxyproline; musculoskeletal disorder diagnosis; nutrition related tag; osteocalcin; osteoporosis; thyroid function

This study of patients with osteoporosis comprises a systematic outpatient and or inpatient assessment of a careful history for risk factors, state of bone (bone density in spine, proximal femur and radius), skeletal activity (serum osteocalcin, alkaline phosphatase, urinary hydroxyproline, iliac bone biopsy), and seconday causes of bone loss (e.g. thyroid function, adrenal status). The ultimate goal is to develop a "metabolic classification" of osteoporosis.

这项骨质疏松症患者的研究包括一个系统的 对门诊和/或住院患者的病史进行仔细的风险评估 因素、骨状态（脊柱、股骨近端和 桡骨），骨骼活性（血清骨钙素，碱性磷酸酶， 尿羟脯氨酸，髂骨活检），和第二个原因骨 损失（例如甲状腺功能、肾上腺状态）。 最终目标是 制定骨质疏松症的“代谢分类”。