K-MAG FACILITATED STONE FRAGMENT DISCHARGE DURING LITHOTRIPSY

本研究的目的是确定K-Mag治疗是否 可减轻“结石”（输尿管结石阻塞 碎片），并减少体外循环后的残余结石量 压电碎石术 该提案将检验以下假设： K-Mag治疗将通过提高尿 镁和柠檬酸盐水平。 尿液中这些“抑制剂”的增加 可以防止碎石结块而且 钙与柠檬酸盐的络合和草酸与镁的络合可以 导致结石质量减少。 上述行动可能被夸大， K-Mag治疗导致尿pH值升高。

The objective of this study is to determine whether K-Mag treatment would alleviate "steinstrasse" (obstruction of the ureter with stone fragments) and reduce residual stone mass following extracorporeal piezoelectric lithotripsy. The proposal will test the hypothesis that K-Mag treatment would meet the above expectations, by raising urinary magnesium and citrate levels. The rise in these "inhibitors" in urine would prevent agglomeration of stone fragments. Moreover, the complexation of calcium by citrate and that of oxalate by magnesium may lead to a reduced stone mass. the above actions may be exaggerated by an increase in urinary pH occuring from K-Mag therapy.