LONG TERM MANAGEMENT OF NEPHROLITHIASIS--CLINICAL RESPONSE AND HAZARDS

肾结石的长期治疗——临床反应和危险

• 批准号: 6567635
• 负责人: MARGARET S. PEARLE
• 金额: $ 32.14万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-12-01 至 2002-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6567635
• 关键词: clinical research; human subject; human therapy evaluation; kidney disorder chemotherapy; longitudinal human study; nephrolithiasis

This long-term project continues to refine the selective therapy of nephrolithiasis, wherein different drugs are provided specifically for the underlying physiologic-metabolic derangement. Using a variety of treatment programs, new stone formation could be reduced individually in 90% of patients, remission obtained in 80%, dissolution of calcium stones achieved (with potassium citrate), and need for surgery of newly formed stones drastically reduced.

这一长期项目将继续完善选择性治疗， 肾结石，其中提供了不同的药物专门用于 潜在的生理代谢紊乱 使用各种 治疗方案，新的结石形成可以单独减少 在90%的患者中，80%获得缓解，钙溶解 获得结石（使用柠檬酸钾），需要进行新的手术 形成的石头急剧减少。