Nine mega-pixel digital mammography display workstation

九兆像素数字乳腺X线摄影显示工作站

• 批准号: 6576952
• 负责人: Guy Marie Besson
• 金额: $ 9.96万
• 依托单位: FISCHER IMAGING CORPORATION
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-23 至 2003-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6576952
• 关键词: bioimaging /biomedical imaging; clinical research; computer graphics /printing; computer network; computer program /software; computer system design /evaluation; computer system hardware; digital imaging; female; human data; image enhancement; mammography; optics

DESCRIPTION (provided by applicant): Phase I: This application is devoted to the development and evaluation of a nine mega-pixel digital mammography workstation. The long-term objective is to provide radiologists with a high-resolution, high-luminance, state-of-the-art review workstation to improve the clinical acceptance of full-field digital mammography. Essential to the realization of this objective is the implementation of display solutions with image quality superior to that of current CRT displays, supported by an integrated platform of software tools to guarantee easy examination flow and efficient examination review. The following specific aims pertain to phase I of this application. (1) Modification of a current review workstation to implement a prototype flat-panel workstation from which to conduct the AMLCD flat-panel physics characterization. (2) Development of the platform architecture and software specifications. (3) Complete flat-panel characterization per the standard guidelines developed by the American Association of Physicists in Medicine task group 18. (4) Definition of the optimal luminance operating points and associated parameters, for optimal display of grayscale mammograms. (5) Development of the workstation advanced functionality specifications, including dual flat-panel display and automatic flat-panel rotation between landscape and portrait mode. Phase II: This application is devoted to the development and evaluation of a nine mega-pixel digital mammography workstation. The long-term objective is to provide radiologists with a high-resolution, high-luminance, state-of-the-art review workstation to improve the clinical acceptance of full-field digital mammography. Essential to the realization of this objective is the implementation of display solutions with image quality superior to that of current CRT displays, supported by an integrated platform of software tools to guarantee easy examination flow and efficient examination review. The following specific aims pertain to phase II of this application. (l) System design and integration. A significant part of the phase IT efforts will be devoted to engineering development work associated with the implementation of the review workstation architecture and software as defined in phase I. The main components of the RWS include the main computer, the graphics adapter cars, the software drivers for the graphics cards, and the main application software. (2) System optimization: psychophysics experiments to ascertain the impact of unique LCD characteristics on visual perception (including definition of the luminance operating range for optimal image display). (3) Pre-clinical evaluation and optimization with respect to the examination process flow. (4) Clinical validation: reader study for the mammography screening exam, conducted under two conditions: with CRT displays, and with fiat-panel displays. The measured outcomes will be area under the ROC curve, sensitivity, specificity, and interpretation time.

描述（由申请人提供）：第I阶段：本申请致力于开发和评价9兆像素数字乳腺X射线摄影工作站。长期目标是为放射科医生提供高分辨率、高亮度、最先进的审查工作站，以提高全视野数字乳腺X射线摄影的临床接受度。实现这一目标的关键是实施图像质量上级当前CRT显示器的显示解决方案，并由软件工具的集成平台提供支持，以确保轻松的检查流程和高效的检查审查。以下具体目标属于本申请的第一阶段。(1)修改当前审查工作站，以实现原型平板工作站，从该工作站进行AMLCD平板物理表征。(2)制定平台架构和软件规格。(3)根据美国医学物理学家协会第18任务组制定的标准指南完成平板表征。(4)定义最佳亮度工作点和相关参数，以实现灰度乳腺X线照片的最佳显示。(5)开发工作站高级功能规格，包括双平板显示器和在横向和纵向模式之间自动旋转平板。 第二阶段：该应用程序致力于开发和评估一个9百万像素的数字乳腺X射线摄影工作站。长期目标是为放射科医生提供高分辨率、高亮度、最先进的审查工作站，以提高全视野数字乳腺X射线摄影的临床接受度。实现这一目标的关键是实施图像质量上级当前CRT显示器的显示解决方案，并由软件工具的集成平台提供支持，以确保轻松的检查流程和高效的检查审查。以下具体目标与本申请的第二阶段有关。(l)系统设计和集成。阶段IT工作的一个重要部分将致力于与第一阶段定义的审查工作站架构和软件的实施相关的工程开发工作。RWS的主要组件包括主计算机、图形适配器汽车、图形卡的软件驱动程序和主应用程序软件。(2)系统优化：心理物理学实验，以确定独特的LCD特性对视觉感知的影响（包括定义最佳图像显示的亮度工作范围）。(3)检查流程的临床前评估和优化。(4)临床验证：乳房X线摄影筛查检查的读片员研究，在两种条件下进行：CRT显示器和平板显示器。测量的结果将是ROC曲线下面积、灵敏度、特异性和解释时间。