CHILD PSYCHIATRY INTERVENTION RESEARCH CENTER

儿童精神病学干预研究中心

• 批准号: 6539014
• 负责人: DAVID SHAFFER
• 金额: $ 148.45万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-24 至 2004-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6539014
• 关键词: behavioral /social science research tag; biomedical facility; child mental disorders; child psychology; clinical research; human subject; human therapy evaluation; psychopharmacology; psychotherapy

This is an application for a Child Psychiatry Intervention Research Center (CPIRC) at New York State Psychiatric Institute. The CPIRC comprises: 1) The Central (Administrative) Core (Director: David Shaffer, M.D.) will perform administrative functions for all Cores, distribute small grants, oversee protocols to insure consumer-sensitive practice, insure coordination between the locally based NIMH Research Unit for Pediatric Psychopharmacology (RUPP), the Ruane Early-Diagnosis Center, and if funded the Anxiety Disorders IRC, will maintain a local Area Network (LAN) to serve all CPIRC users; 2) a Clinical Core (PI: Rachel Klein, Ph.D.) will recruit and screen subjects for treatment studies and will provide post-protocol care; 3) a Psycho-therapy Core (PI: Myrna Weissman, Ph.D.) will provide training and archival materials for manualized psychotherapies; 4) a Biostatistics, Measurement, Effectiveness Evaluation Core (PI: Andrew Leon, Ph.D.) will provide consultation on biostatistics, and research design, that will advise investigators on planning and conducting of effectiveness studies that will advise and train research staff on measurement choice and will manage and customize entry into a uniform database; and 5) a Psychopharmacology Core (PI: Laurence Greenhill, M.D.) that will monitor safety parameters, provide manuals to standardize psychopharmacology studies, will provide training and will facilitate pharmacological and basic science studies related to treatment response. Over the past four years, there has been a Child Psychiatry CRC that performed some but not all the treatment related functions that will be carried out by the CPIC that CRC screened over 1,698 individuals and referred over 718 to treatment protocols, provided consultation on 75 research projects, provided over 200 consultations related to publications and research-grant applications, and given courses whose combined audiences numbered in the hundreds. CRC users were productive: over a 4 year period wrote 367 publications that related to Center activities. This flourishing research environment, will be maintained by the CPIRC. The CPIRC will start life with a large number of experienced researchers and 28 funded treatment protocols. It will provide the infrastructure necessary for successful recruitment, sophisticated design badly needed in a field characterized by the widespread use of medical and psychotherapies of unproven value and safety for children and teens.

这是纽约州精神病学研究所儿童精神病学干预研究中心(CPIRC)的申请书。CPIRC包括：1)中央(行政)核心(主任：David Shaffer，M.D.)将履行所有核心的行政职能，分发小额赠款，监督协议以确保消费者敏感的做法，确保当地的NIMH儿科精神药理学研究单位(RUPP)、Ruane早期诊断中心和焦虑障碍IRC之间的协调，如果资助焦虑症IRC，将维护一个局域网(LAN)，为所有CPIRC用户服务；2)临床核心(PI：Rachel Klein，Ph.D.)将招募和筛选受试者进行治疗研究，并提供礼仪后护理；3)心理治疗核心(PI：Myrna Weissman，Ph.D.)将为人工心理治疗提供培训和档案材料；4)生物统计、测量、效果评估核心(PI：Andrew Leon，博士)将提供关于生物统计学和研究设计的咨询，将就有效性研究的规划和进行提供建议，这些研究将就测量选择提供建议和培训研究人员，并将管理和定制进入统一数据库的条目；以及5)精神药理学核心(PI：Laurence Greenhill，M.D.)这将监测安全参数，提供标准化精神药理学研究的手册，将提供培训，并将促进与治疗反应有关的药理学和基础科学研究。在过去的四年里，有一个儿童精神病学儿童研究中心履行了儿童精神病学委员会将要执行的一些但不是所有与治疗有关的职能，儿童精神疾病研究中心对1,698多人进行了筛查，转介了718多人接受治疗方案，为75个研究项目提供咨询，提供了200多个与出版物和研究资助申请有关的咨询，并提供了受众总数达数百人的课程。儿童权利中心的用户是富有成效的：在四年的时间里，编写了367份与中心活动有关的出版物。这一蓬勃发展的研究环境将由CPIRC保持。CPIRC将以大量经验丰富的研究人员和28项资助的治疗方案开始运作。它将为成功招募提供必要的基础设施，这是一个以广泛使用对儿童和青少年具有未经证实的价值和安全性的医疗和心理治疗为特点的领域迫切需要的复杂设计。