Core--Research Methods

核心--研究方法

• 批准号: 7439036
• 负责人: DAVID SHAFFER
• 金额: $ 22.09万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7439036
• 关键词: Adolescent; Adverse effects; Adverse event; Area; Biological; Child; Communities; Development; Diagnosis; Educational Materials; Effectiveness; Evaluation; Feeling suicidal; Genetic; Impairment; Intervention Studies; Magnetic Resonance Imaging; Measurement; Measures; Mediator of activation protein; Methods; Parents; Patients; Perception; Research Methodology; Resources; Symptoms; Techniques; Teenagers; Testing; base; design; experience; improved; programs; psychoeducational; response

The function of the Research Methods Core will be to coordinate and support the development of selected research methodologies and materials. The choice of projects described below has been determined by our perception of need and by the availability of skilled and experienced experts in two areas, which are: 1. The Development of Measures and Materials for Intervention Research 2. Developing reliable but brief and sensitive measures of change and diagnosis that will reduce the evaluation burden in effectiveness studies; 3. Developing methods to reliably record adverse events in treatment studies; 4. Developing quantitative measures of suicide ideation; and 5. Developing a resource to test and modify psychoeducational materials for child and adolescent patients and their parents. 6. The Study of Biological Mediators and Moderators of Treatment Response 7. The study of the neuro-anatomical and neuro-functional correlates of changes resulting from treatment using MRI; and 8. Genotypic studies of possible genetic moderators of treatment response.

研究方法核心的职能是协调和支持 开发选定的研究方法和材料。下文所述项目的选择是根据我们对需求的认识以及两个领域的熟练和经验丰富的专家的可用性确定的，这两个领域是： 1.干预性研究方法与材料的发展 2.制定可靠但简短和敏感的变化和诊断措施， 成效研究的评价负担; 3.开发可靠记录治疗研究中不良事件的方法; 4.制定自杀意念的量化措施;以及 5.开发资源，以测试和修改心理教育材料的儿童和青少年患者及其父母。 6.治疗反应的生物介导因子和调节因子研究 7.神经解剖学研究由神经系统损伤引起的神经解剖学和神经功能变化的相关性的学科 使用MRI进行治疗;以及 8.治疗反应的可能遗传调节因子的基因型研究。