HIV/AIDS Research and Training in Northern Thailand

泰国北部的艾滋病毒/艾滋病研究和培训

• 批准号: 6560148
• 负责人: THIRA SIRISANTHANA
• 金额: $ 5.34万
• 依托单位: CHIANG MAI UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2004-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6560148
• 关键词: AIDS; AIDS education /prevention; HIV infections; health science research support; human immunodeficiency virus 1; southeast Asia; training

DESCRIPTION: Thailand has been successful in preventing the transmission of HIV in commercial sex settings. Despite the decline in HIV incidence, the burden of HIV infection will be a major problem for the coming generation. There are more than 750,000 persons living with HIV/AIDS in Thailand. Transmission in IDUs is still a significant problem, and transmission between spouses and via casual sex is on the rise. Less than 1% of persons living with HIV/AIDS in Thailand are on antiretroviral treatment. The cost of antiretroviral drugs is coming down, and there is a need to train physicians to be familiar with antiretroviral therapy. There is a need to find the best strategy to manage opportunistic infections in the era of antiretroviral therapy. In addition, there is a need to study the molecular epidemiology of HIV-1 in preparation for vaccine trials. The aim of this project is to plan the development of a regional capacity to initiate and sustain an ongoing research effort as well as the development of a regional training center in the prevention and care of HIV/AIDS. Three CIPRA cores namely administrative, laboratory, and training core will be established. The investigators will plan to submit an application for the next level of CIPRA support. It will include research in molecular epidemiology, care of opportunistic infection in the era of antiretroviral treatment, and antiretroviral therapy in children among others. It will also address other behavioral and biomedical (including vaccine) intervention in the prevention and care of HIV/AIDS that are relevant to the country's problems.

描述：泰国已经成功地防止了商业性别环境中的艾滋病毒传播。尽管艾滋病毒发病率下降，但艾滋病毒感染的负担对于即将到来的一代人来说将是一个主要问题。泰国有75万多人患有艾滋病毒/艾滋病。 IDU中的传播仍然是一个重大问题，配偶与随意性之间的传播正在上升。泰国有艾滋病毒/艾滋病的人中，只有不到1％的人接受抗逆转录病毒治疗。抗逆转录病毒药物的成本降低了，有必要培训医生熟悉抗逆转录病毒疗法。在抗逆转录病毒疗法时代，有必要找到管理机会性感染的最佳策略。此外，有必要研究HIV-1的分子流行病学，以准备疫苗试验。该项目的目的是计划发展和维持正在进行的研究工作的区域能力，以及在预防和护理艾滋病毒/艾滋病的预防和护理中开发区域培训中心。将建立三个CIPRA核心，即行政，实验室和培训核心。调查人员将计划提交一项新的CIPRA支持申请。它将包括分子流行病学研究，抗逆转录病毒治疗时代的机会感染以及儿童抗逆转录病毒疗法的研究。它还将解决与该国问题相关的艾滋病毒/艾滋病的预防和护理的其他行为和生物医学（包括疫苗）。