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Medical Image Presentation: Structural Image Analysis

医学图像演示：结构图像分析

基本信息

批准号：
6470776
负责人：
STEPHEN M PIZER
金额：
$ 139.71万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
1988
资助国家：
美国
起止时间：
1988-07-03 至 2007-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6470776
关键词：
bioimaging /biomedical imaging clinical research computer data analysis human data image processing method development

项目摘要

DESCRIPTION (provided by applicant) Following strong successes in all 3 projects of our present program, we have decided to increase the focus of our program project by building our new program on one of them and are seeking separate funding for the other two. In particular, we focus this program on segmentation and discrimination of the geometric structure of 3D objects in medical images by our principled and innovative methods working at multiple levels of scale and based on training image sets. The program consists of four projects and three cores. One of the projects focuses on development and extension of image analysis methods based on single and multiple object models at multiple levels of scale, with the middle levels of scale specifically designed to represent the figural aspects of objects. Because of the successes of our image analysis methodology, it is now time for three projects to pursue medical uses of such methods. Two of these three focus on the segmentation of structures in the brain and discrimination of disease from their geometric structure in relation to the diagnosis of mental illnesses. The other medical project continues our present program's focus on radiotherapy treatment planning. To support the evaluation of the image analysis methods both geometrically and in medical terms, we continue the core on biostatistics, and we add a core on the development of methodology for validation of image analysis methods. Finally, a facilities and administration core provides infrastructure for the other projects.

描述（由申请人提供）在我们目前计划的所有3个项目取得巨大成功之后，我们决定通过建立我们的新项目来增加我们项目的重点其中一项计划，并正在为其他两项寻求单独的资金。特别是，我们专注于这个程序的分割和歧视，的几何结构的三维物体在医学图像中，我们的原则和在培训的基础上，在多个层面上采用创新方法图像集。该计划包括四个项目和三个核心。之一该项目的重点是图像分析方法的开发和推广基于单个和多个对象模型在多个级别的规模，中间层次的规模专门设计来代表人物物体的方面。因为我们成功的图像分析方法，现在是三个项目追求医疗用途的时候了，方法.这三个中的两个侧重于结构的分割，大脑和疾病的区别从他们的几何结构的关系精神疾病的诊断另一个医疗项目继续我们的目前计划的重点是放射治疗计划。支持图像分析方法的几何和医学评价我们继续生物统计学的核心，我们增加了一个核心，开发验证图像分析方法的方法。最后，设施和管理核心为其他项目

项目成果

期刊论文数量（67）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Visual increment and decrement threshold curves as a function of luminance range and noise in simulated computed tomographic scans.

视觉增量和减量阈值曲线作为模拟计算机断层扫描中亮度范围和噪声的函数。

DOI：
10.1097/00004424-199208000-00007
发表时间：
1992
期刊：
Investigative radiology
影响因子：
6.7
作者：
Klymenko,V;Johnston,RE;Pizer,SM
通讯作者：
Pizer,SM

Medial-node models to identify and measure objects in real-time 3-D echocardiography.

用于在实时 3D 超声心动图中识别和测量对象的内侧节点模型。

DOI：
10.1109/42.811314
发表时间：
1999
期刊：
IEEE transactions on medical imaging
影响因子：
10.6
作者：
Stetten,GD;Pizer,SM
通讯作者：
Pizer,SM

A linear exponent AR(1) family of correlation structures.

DOI：
10.1002/sim.3928
发表时间：
2010-07-30
期刊：
STATISTICS IN MEDICINE
影响因子：
2
作者：
Simpson, Sean L.;Edwards, Lloyd J.;Muller, Keith E.;Sen, Pranab K.;Styner, Martin A.
通讯作者：
Styner, Martin A.

Figure and ground in space and time: 2. Frequency, velocity, and perceptual organization.

空间和时间上的图形和地面：2.频率、速度和感知组织。