WEB BASED KINETIC ANALYSIS OF BREAST MRI

基于网络的乳房 MRI 动力学分析

• 批准号: 6657650
• 负责人: MARK A ELLIOTT
• 金额: $ 22.55万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-01 至 2003-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6657650
• 关键词: bioengineering /biomedical engineering; bioimaging /biomedical imaging; biomedical resource; female; health care; human subject; magnetic resonance imaging; technology /technique

High resolution imaging techniques using noninvasive modalities such as magnetic resonance imaging have been pursued as in vivo cancer screening techniques in an attempt to eliminate the invasive nature of surgical biopsy. The resolution and field of view attainable with magnetic resonance imaging has been limited in the past due to aliasing of the image. We present here a technique that uses this aliasing to produce high resolution images with larger matrix sizes than are currently available. It is performed in two dimensions, the frequency encoding and phase encoding direction, and the image is allowed to alias in both. The individual, aliased fields of view can be recovered by encoding the spatial information within the plane of the image using Hadamard methods. These images may then be tiled to obtain a composite image with high spatial resolution and a large field of view. This technique is demonstrated using two-dimensional and three-dimensional in vivo imagin g of the human brain and breast.

使用非侵入性方式的高分辨率成像技术 例如磁共振成像一直被作为体内癌症进行研究 筛查技术，试图消除侵袭性 外科活组织检查。可获得的分辨率和视场 磁共振成像在过去一直受到限制，因为 图像的锯齿。我们在这里展示了一种技术，它使用了 混叠以生成具有更大矩阵大小的高分辨率图像 比目前可用的更多。它在两个维度上执行，即 频率编码和相位编码方向，图像 允许在两者中使用别名。单独的、混叠的视场可以 通过将空间信息编码在 该图像使用Hadamard方法。然后可以将这些图像平铺到 获得高空间分辨率的合成图像和较大的 视野。这项技术是用二维的 以及人脑和乳房的三维活体成像。