RETROSPECTIVE QUALITY ASSESSMENT OF FMRI DATA

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 功能磁共振成像(FMRI)是磁共振成像的一种专门应用，它可以定位 与常规临床研究相比，对扫描仪性能和稳定性的额外要求。 由于功能磁共振成像试图识别在存在特定刺激或 任务、不稳定或MRI信号中的过度噪声可能会导致假阳性或 激活检测结果为阴性。当应用于组比较时，通常是这样的 在疾病或药物干预的研究中，随着时间的推移数据质量的变化可以 被误解为不同群体之间的差异。对功能磁共振成像的要求通常超过 商业制造商质量评估(QA)和 预防性维护。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Functional magnetic resonance imaging (fMRI) is a specialized application of MRI which places additional demands on scanner performance and stability compared to routine clinical studies. Since fMRI attempts to identify brain regions activated in the presence of particular stimuli or tasks, instabilities or excessive noise in the MRI signal can lead to either false positive or negative detection of activation. When applied to group comparisons as is commonly the case in the study of disease or pharmacological interventions, changes in data quality over time can be misinterpreted as differences between groups. The requirements for fMRI generally exceed the specifications covered by commercial manufacturer quality assessment (QA) and preventative maintenance.