Modifying Stress in Hypertensive African American Women

改变高血压非洲裔美国女性的压力

• 批准号: 6639310
• 负责人: MARY S WEBB
• 金额: $ 13.44万
• 依托单位: UNIVERSITY OF SOUTH FLORIDA
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-05-15 至 2005-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6639310
• 关键词: African American; angers; autogenic training; behavior modification; behavioral /social science research tag; behavioral medicine; clinical research; cognitive behavior therapy; coping; female; human subject; human therapy evaluation; hypertension; outcomes research; patient care management; psychological stressor; questionnaires; relaxation; women's health

A major cause of the disproportionate rate of coronary heart disease and other cardiovascular disease in African American women is the high prevalence of hypertension in this population. Compared with Whites, hypertension develops earlier in life and average blood pressures are much higher in African Americans. Evidence suggests that the likelihood of developing hypertension is increased among individuals who experience continued psychological stress. Studies on emotions and behaviors associated with the stress process indicate that anger, anger expression style, and coping behaviors have particular relevance for hypertensive African American women. Cognitive behavioral therapy, a type of stress management, emphasizes improving the person's competency in handling significant aspects of the surrounding world. The core components of a cognitive behavioral intervention are arousal/ emotional reduction (relaxation) and cognitive mediation. The long-term goal of the applicant is to obtain extramural funding to evaluate a nonpharmacological intervention to assist African American women in modifying their cognitive and behavioral responses to stress. To accomplish this goal, the applicant will pursue a career development program consisting of (a) clinical management of hypertension, (b) clinical trials research, (c) data analyses and management, and (d) cultural competence in research. This training will be applied to the specific aims of the research program: (a) Design and pilot two cognitive/ behavioral interventions (relaxation and cognitive mediation) for hypertensive African American women (N=90), (b) Determine the effectiveness of the two approaches as compared to a traditional educational program, (c) Compare the relative effectiveness of the two approaches (relaxation and cognitive mediation), and (d) Develop a competitive RO1 research application based on findings of the pilot intervention. Study variables for the research plan will be evaluated with State-Trait Anger Expression Inventory, the Personal Strain Questionnaire, and the Coping Resources Questionnaire. waist/ hip ratios, and blood pressure. An orthogonal set of single-degree-of-freedom interaction contrasts will be used to determine the effectiveness of the two approaches as compared to a traditional educational program. A single-degree-of-freedom interaction contrast will be used to compare the relative effectiveness of the two approaches (relaxation and cognitive mediation). Findings from the pilot interventions will be used to refine and develop a RO1 proposal for consideration of extramural funding.

非洲裔美国妇女中冠心病和其他心血管疾病率不成比例的主要原因是该人群中高血压的高流行。与白人相比，高血压在生活中发展较早，非裔美国人的平均血压要高得多。有证据表明，在持续心理压力的个体中，出现高血压的可能性增加。关于与压力过程相关的情绪和行为的研究表明，愤怒，愤怒的表达方式和应对行为与高血压的非裔美国妇女特别相关。认知行为疗法是一种压力管理，强调提高人们在处理周围世界重要方面的能力。认知行为干预的核心组成部分是唤醒/情绪减少（放松）和认知中介。申请人的长期目标是获得校外资金，以评估非药理学干预措施，以帮助非洲裔美国妇女改变其对压力的认知和行为反应。为了实现这一目标，申请人将追求一项职业发展计划，包括（a）高血压临床管理，（b）临床试验研究，（c）数据分析和管理以及（d）研究中的文化能力。 This training will be applied to the specific aims of the research program: (a) Design and pilot two cognitive/ behavioral interventions (relaxation and cognitive mediation) for hypertensive African American women (N=90), (b) Determine the effectiveness of the two approaches as compared to a traditional educational program, (c) Compare the relative effectiveness of the two approaches (relaxation and cognitive mediation), and (d) Develop a competitive RO1 research application based on试点干预的结果。研究计划的研究变量将通过州特征愤怒表达清单，个人应变问卷和应对资源问卷进行评估。腰围/髋关节和血压。与传统的教育计划相比，将使用一组正交的单度自由相互作用对比度来确定两种方法的有效性。单度相互作用的对比度将用于比较两种方法的相对有效性（放松和认知介导）。试点干预措施的发现将用于完善和制定RO1提案，以考虑壁外资金。