Constructing summary statistics from composite likelihoods for approximate Bayesian computation
从复合可能性构建汇总统计数据以进行近似贝叶斯计算
基本信息
- 批准号:2123488
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:英国
- 项目类别:Studentship
- 财政年份:2018
- 资助国家:英国
- 起止时间:2018 至 无数据
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
To generate realisations from a posterior distribution, methods such as Markov chain Monte Carlo and sequential Monte Carlo rely on evaluation of the likelihood function. However, for many complex models the likelihood is computationally intractable. Approximate Bayesian computation (ABC) and composite likelihoods can be useful tools to allow inference to proceed when the likelihood is not available. When data can easily be simulated from a model, ABC provides an approximation to the posterior distribution, avoiding evaluation of the likelihood, by measuring the similarity between the observed data and simulated data. A basic ABC rejection scheme simulates data using parameter values sampled from the prior distribution, and accepts the parameter values if the distance between vectors of summary statistics for the observed data and simulated data is smaller than some pre-defined tolerance. The choice of summary statistics used within ABC can greatly affect the quality of the approximate inference. If the full likelihood is unavailable, but evaluation of the likelihood for some subsets of the data is straightforward, then a composite likelihood can be used to replace the full likelihood. A composite likelihood is a weighted product of valid likelihood terms, corresponding to a collection of marginal or conditional events. The weights in a composite likelihood can be set equal and ignored. However, a carefully selected set of weights can improve statistical efficiency. If a composite likelihood is used directly in Bayes' theorem the variability in the posterior is often greatly underestimated, with the composite posterior being excessively concentrated. Calibration methods have been proposed to adjust the composite likelihood for use in Bayes' theorem. However, such methods can result in the calibrated composite posterior being too dispersed. Previous work combining composite likelihoods and ABC suggests using the composite score as the summary statistic for ABC. To implement this approach a suitable composite likelihood, including the associated weights, must first be chosen. For some models there may not be a clear choice for the weights, or there may be several candidate composite likelihoods to choose from. The aims of this project are: to explore new methods for constructing summary statistics for ABC from composite likelihoods, to develop methods for constructing summary statistics such that the associated weights in the composite likelihood can be chosen automatically, to develop techniques that combine multiple composite likelihoods for contribution to summary statistics, and to ultimately develop a thorough methodology that will allow automatic construction of a summary statistic to use within ABC to allow efficient and accurate inference for models for which at least one composite likelihood can be defined. Possible applications for this new methodology include spatial extremes and space-time models.
为了从后验分布生成实现,诸如马尔可夫链蒙特卡罗和顺序蒙特卡罗的方法依赖于似然函数的评估。然而,对于许多复杂的模型,这种可能性在计算上是难以处理的。近似贝叶斯计算(ABC)和复合似然可以是有用的工具,允许推理时,可能性是不可用的。当数据可以很容易地从模型中模拟时,ABC通过测量观察数据和模拟数据之间的相似性,提供了对后验分布的近似,避免了对可能性的评估。基本的ABC拒绝方案使用从先验分布采样的参数值来模拟数据,并且如果观察数据和模拟数据的汇总统计量的向量之间的距离小于某个预定义的容差,则接受参数值。ABC中使用的汇总统计量的选择可以极大地影响近似推理的质量。如果完全似然不可用,但对数据的某些子集的似然的评估是直接的,则可以使用复合似然来代替完全似然。复合似然是有效似然项的加权乘积,对应于边际或条件事件的集合。复合似然中的权重可以设置为相等并忽略。然而,仔细选择一组权重可以提高统计效率。如果在贝叶斯定理中直接使用复合似然,则后验的可变性往往被大大低估,复合后验过度集中。校准方法已经被提出来调整用于贝叶斯定理的复合似然。然而,这样的方法可能导致校准的复合后验过于分散。以前的工作结合复合似然和ABC建议使用的综合得分作为ABC的汇总统计。为了实现这种方法,必须首先选择合适的复合似然,包括相关联的权重。对于某些模型,权重可能没有明确的选择,或者可能有几个候选复合可能性可供选择。该项目的目标是:探索用于从复合似然构造ABC的汇总统计量的新方法,开发用于构造汇总统计量的方法,使得可以自动选择复合似然中的相关联权重,开发联合收割机多个复合似然以贡献于汇总统计量的技术,并最终开发出一种全面的方法,该方法将允许自动构建在ABC内使用的汇总统计量,以允许对模型进行有效和准确的推断,其中至少一个复合可能性可以被定义。这种新方法的可能应用包括空间极值和时空模型。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
其他文献
吉治仁志 他: "トランスジェニックマウスによるTIMP-1の線維化促進機序"最新医学. 55. 1781-1787 (2000)
Hitoshi Yoshiji 等:“转基因小鼠中 TIMP-1 的促纤维化机制”现代医学 55. 1781-1787 (2000)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
LiDAR Implementations for Autonomous Vehicle Applications
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
吉治仁志 他: "イラスト医学&サイエンスシリーズ血管の分子医学"羊土社(渋谷正史編). 125 (2000)
Hitoshi Yoshiji 等人:“血管医学与科学系列分子医学图解”Yodosha(涉谷正志编辑)125(2000)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Effect of manidipine hydrochloride,a calcium antagonist,on isoproterenol-induced left ventricular hypertrophy: "Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,K.,Teragaki,M.,Iwao,H.and Yoshikawa,J." Jpn Circ J. 62(1). 47-52 (1998)
钙拮抗剂盐酸马尼地平对异丙肾上腺素引起的左心室肥厚的影响:“Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('', 18)}}的其他基金
An implantable biosensor microsystem for real-time measurement of circulating biomarkers
用于实时测量循环生物标志物的植入式生物传感器微系统
- 批准号:
2901954 - 财政年份:2028
- 资助金额:
-- - 项目类别:
Studentship
Exploiting the polysaccharide breakdown capacity of the human gut microbiome to develop environmentally sustainable dishwashing solutions
利用人类肠道微生物群的多糖分解能力来开发环境可持续的洗碗解决方案
- 批准号:
2896097 - 财政年份:2027
- 资助金额:
-- - 项目类别:
Studentship
A Robot that Swims Through Granular Materials
可以在颗粒材料中游动的机器人
- 批准号:
2780268 - 财政年份:2027
- 资助金额:
-- - 项目类别:
Studentship
Likelihood and impact of severe space weather events on the resilience of nuclear power and safeguards monitoring.
严重空间天气事件对核电和保障监督的恢复力的可能性和影响。
- 批准号:
2908918 - 财政年份:2027
- 资助金额:
-- - 项目类别:
Studentship
Proton, alpha and gamma irradiation assisted stress corrosion cracking: understanding the fuel-stainless steel interface
质子、α 和 γ 辐照辅助应力腐蚀开裂:了解燃料-不锈钢界面
- 批准号:
2908693 - 财政年份:2027
- 资助金额:
-- - 项目类别:
Studentship
Field Assisted Sintering of Nuclear Fuel Simulants
核燃料模拟物的现场辅助烧结
- 批准号:
2908917 - 财政年份:2027
- 资助金额:
-- - 项目类别:
Studentship
Assessment of new fatigue capable titanium alloys for aerospace applications
评估用于航空航天应用的新型抗疲劳钛合金
- 批准号:
2879438 - 财政年份:2027
- 资助金额:
-- - 项目类别:
Studentship
Developing a 3D printed skin model using a Dextran - Collagen hydrogel to analyse the cellular and epigenetic effects of interleukin-17 inhibitors in
使用右旋糖酐-胶原蛋白水凝胶开发 3D 打印皮肤模型,以分析白细胞介素 17 抑制剂的细胞和表观遗传效应
- 批准号:
2890513 - 财政年份:2027
- 资助金额:
-- - 项目类别:
Studentship
Understanding the interplay between the gut microbiome, behavior and urbanisation in wild birds
了解野生鸟类肠道微生物组、行为和城市化之间的相互作用
- 批准号:
2876993 - 财政年份:2027
- 资助金额:
-- - 项目类别:
Studentship
相似海外基金
Novel methods to improve the utility of genomics summary statistics
提高基因组学汇总统计效用的新方法
- 批准号:
10646125 - 财政年份:2023
- 资助金额:
-- - 项目类别:
Integrative genomic and geospatial analysis of insurance claim, biobank and GWAS summary statistics for complex traits
保险索赔的综合基因组和地理空间分析、生物库和复杂性状的 GWAS 汇总统计
- 批准号:
10595104 - 财政年份:2023
- 资助金额:
-- - 项目类别:
Methods for leveraging family-based designs and summary data to elucidate complex trait genetics
利用基于家族的设计和汇总数据来阐明复杂性状遗传学的方法
- 批准号:
10713748 - 财政年份:2023
- 资助金额:
-- - 项目类别:
A summary-data-based Mendelian randomization method with application to correlated lipidomic data
基于汇总数据的孟德尔随机化方法及其应用于相关脂质组学数据
- 批准号:
10709485 - 财政年份:2022
- 资助金额:
-- - 项目类别:
Expanding effective report-back of environmental exposures among new researchers and clinic-based studies
扩大新研究人员和临床研究中环境暴露的有效报告
- 批准号:
10570911 - 财政年份:2022
- 资助金额:
-- - 项目类别:
Integrative genomic and geospatial analysis of insurance claim, biobank and GWAS summary statistics for complex traits
保险索赔的综合基因组和地理空间分析、生物库和复杂性状的 GWAS 汇总统计
- 批准号:
10688692 - 财政年份:2022
- 资助金额:
-- - 项目类别:
Using External Reference Panel and Single-Variant Summary Statistics for Rare-Variant Aggregation Tests
使用外部参考面板和单变体汇总统计进行稀有变体聚合测试
- 批准号:
474156 - 财政年份:2022
- 资助金额:
-- - 项目类别:
Studentship Programs
Expanding effective report-back of environmental exposures among new researchers and clinic-based studies
扩大新研究人员和临床研究中环境暴露的有效报告
- 批准号:
10372876 - 财政年份:2022
- 资助金额:
-- - 项目类别:
A summary-data-based Mendelian randomization method with application to correlated lipidomic data
基于汇总数据的孟德尔随机化方法及其应用于相关脂质组学数据
- 批准号:
10424741 - 财政年份:2022
- 资助金额:
-- - 项目类别: