Positron Nano-Dosimetry: Fundamental Measurements of Positron Interactions and their use in State-of-the-Art Modelling of Positron Transport

这一提议将为正电子(电子反粒子)如何与物质相互作用，特别是与具有生物重要性的分子相互作用提供独特的实验和理论信息。这些数据将被用于一套独特的建模方法，这将首次为正电子如何在气体、液体以及最终的软物质中传输提供洞察力。因此，它将对正电子发射断层扫描等诊断工具产生重要影响。这项基础研究还将揭示生命的一个关键“奥秘”--为什么生命的生物构件具有明确的“利手”或手性。

This proposal will provide unique experimental and theoretical information on how positrons, the electron antiparticles, interact with matter, in particular with biologically important molecules. This data will be used in a unique set of modelling approaches which will provide, for the first time, an insight into how positrons are transported through gases, liquids and ultimately, soft matter. It will thus have important ramifications for diagnostic tools such as Positron Emission Tomography. The fundamental research will also shed light on one of the key 'mysteries' of life - why the biological building blocks of life possess a definite " handedness", or chirality.