Microfluidic networks: an in vitro 3D culture system for the investigation of neuron-glial interactions in neruodegeneration.

微流体网络：用于研究神经变性中神经元-胶质细胞相互作用的体外 3D 培养系统。

• 批准号: 2218814
• 金额: --
• 依托单位: University of Nottingham
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2016
• 资助国家: 英国
• 起止时间: 2016 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2218814
• 关键词: Microfluidic; networks; vitro; 3D; culture

The principal goal of the project is to develop a new in vitro microfluidics system for investigating neuron-glial interactions under highly controlled conditions. The system is designed to more closely mimic in vivo conditionsthan current culture methods, with the intention that it can replace the use of ex vivo tissue from transgenic animals as an experimental model for the study of neurodegeneration.

该项目的主要目标是开发一种新的体外微流体系统，用于在高度受控的条件下研究神经元-神经胶质细胞的相互作用。该系统被设计成比目前的培养方法更接近地模拟体内条件，目的是它可以取代使用转基因动物的离体组织作为神经变性研究的实验模型。