Regenerating the kidney by restoring the renal microvasculature

通过恢复肾脏微血管来再生肾脏

• 批准号: 2241997
• 金额: --
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2241997
• 关键词: Regenerating; kidney; restoring; renal; microvasculature

The small vessels within the kidney become damaged in patients with renal disease. This project will attempt to use cells to restore the damaged kidney blood vessels which we predict will then lead to regeneration of the diseased kidney. We will test different sources of cells, administration routes and timing of treatment to determine the optimal therapy to improve kidney disease. If successful, these studies could potentially lead to clinical trials using cell-based therapies for renal regeneration and repair.

肾脏疾病患者的肾脏内的小血管受损。该项目将尝试使用细胞来恢复受损的肾脏血管，我们预测这将导致患病肾脏的再生。我们将测试不同的细胞来源、给药途径和治疗时机，以确定改善肾脏疾病的最佳疗法。如果成功，这些研究可能会导致使用基于细胞的疗法进行肾脏再生和修复的临床试验。