New Directions in Cooperative Catalysis

协同催化的新方向

• 批准号: 2248644
• 金额: --
• 依托单位: CARDIFF UNIVERSITY
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2248644
• 关键词: New; Directions; Cooperative; Catalysis

Cooperative catalysis, in which multiple molecule sites act in concert to activate and transform small molecules, is a growing area of interest. We have previously explored so-called 'frustrated' Lewis pairs in which either the acidic or basic function is based on a transition metal complex. This project will build on these results using new ligand-metal combinations to impart higher functional group tolerance and potentially chirality. Mid-transitional metals will be a focus, since these have a good track record of other transformations in which these characteristics are important. We will study both the fundamental organometallic chemistry of such systems in small molecule activation, especially dynamic behaviour, as well as catalysis.

协同催化，其中多个分子位点协同作用以活化和转化小分子，是一个越来越受关注的领域。我们以前已经探索了所谓的“受挫”刘易斯对，其中酸性或碱性功能是基于过渡金属络合物。该项目将建立在这些结果的基础上，使用新的配体-金属组合来赋予更高的官能团耐受性和潜在的手性。中过渡金属将是一个重点，因为这些金属在这些特征很重要的其他转变中有着良好的记录。我们将研究这两个系统在小分子活化，特别是动态行为，以及催化的基本有机金属化学。