Delta Vision Microscope Model 283 Configuration System

Delta 视觉显微镜 283 型配置系统

基本信息

  • 批准号:
    6440453
  • 负责人:
  • 金额:
    $ 29.63万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2002
  • 资助国家:
    美国
  • 起止时间:
    2002-05-01 至 2003-04-30
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): This shared equipment proposal brings together a diverse group of twelve investigators from multiple Departments at Northwestern University Medical School. The group works on a wide range of organisms that include viruses (Longnecker), bacteria (Seifert) protozoa (Engman and Haldar) and mammalian cells (Borisy. Green, Reddy, Miller). Their studies encompass diverse cellular processes that range from antigen processing, T cell activation, cell migration, junction formation, cell division, adhesion and invasion of pathogens and novel eukaryotic organdlies. The focus of the group is to first examine protein expression, organization and transport in both living and fixed cells/tissues and then correlate protein expression and distributions with cellular events of transport and signaling, as regulated by prokaryotes, lower eukaryotes and mammalian cells. The applications described are in Host-pathogen interactions, Mammalian Cell Biology, Motility, Immunology. The DeltaVision microscope will enable investigators to have : 1) simultaneous acquisition of triple-labeled specimens; 2) higher optical efficiency for light collection system for low intensity specimens; 3) increased resolution (150 nm vs. 200 nm for confocal) for studying details of cell structure; 4) DIC; and 5) visualization of nuclei with UV dyes. This microscope fulfills all of the different experimental requirements of the group. For all eight investigators, experiments with a "leased? DeltaVision microscope or access to a similar microscope at other universities, have resulted in important new cellular insights. The microscope will be centrally located in an existing Imaging Facility that has well established training and technical support programs, and is used over 70 PIs (and an even larger number of affiliated Research Faculty, Postdoctoral Fellows, Graduate Students and Research Associates) from 20 basic science and clinical departments in the Medical School. A DeitaVision microscope on lease has been used by 44 users indicating its demand. The purchase of the DeitaVision microscope will provide a ?state-of-the-art? microscope that can be applied to studying a wide range of applications. It will also enhance scientific interactions between investigators working in diverse areas of biology and human health in the school.
描述(由申请人提供):此共享设备提案带来

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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KASTURI HALDAR其他文献

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{{ truncateString('KASTURI HALDAR', 18)}}的其他基金

Malaria Phosphatase Inhibitors Identified as a Potential New Malaria Treatment
疟疾磷酸酶抑制剂被确定为潜在的新疟疾治疗方法
  • 批准号:
    8476279
  • 财政年份:
    2012
  • 资助金额:
    $ 29.63万
  • 项目类别:
Malaria Phosphatase Inhibitors Identified as a Potential New Malaria Treatment
疟疾磷酸酶抑制剂被确定为潜在的新疟疾治疗方法
  • 批准号:
    8262565
  • 财政年份:
    2012
  • 资助金额:
    $ 29.63万
  • 项目类别:
MECHANISMS OF ERYTHROCYTIC INFECTIONS AND ANEMIA: NHP MODEL MALARIAL ANEMIA
红细胞感染和贫血的机制:NHP 模型疟疾贫血
  • 批准号:
    8172365
  • 财政年份:
    2010
  • 资助金额:
    $ 29.63万
  • 项目类别:
Tubovesicular traffic induced in red cells in plasmodia
疟原虫红细胞中诱导的管泡交通
  • 批准号:
    8054523
  • 财政年份:
    2010
  • 资助金额:
    $ 29.63万
  • 项目类别:
MECHANISMS OF ERYTHROCYTIC INFECTIONS AND ANEMIA: NHP MODEL MALARIAL ANEMIA
红细胞感染和贫血的机制:NHP 模型疟疾贫血
  • 批准号:
    7958179
  • 财政年份:
    2009
  • 资助金额:
    $ 29.63万
  • 项目类别:
MECHANISMS OF ERYTHROCYTIC INFECTIONS AND ANEMIA: NHP MODEL MALARIAL ANEMIA
红细胞感染和贫血的机制:NHP 模型疟疾贫血
  • 批准号:
    7715763
  • 财政年份:
    2008
  • 资助金额:
    $ 29.63万
  • 项目类别:
MECHANISMS OF ERYTHROCYTIC INFECTIONS AND ANEMIA: NHP MODEL MALARIAL ANEMIA
红细胞感染和贫血的机制:NHP 模型疟疾贫血
  • 批准号:
    7562623
  • 财政年份:
    2007
  • 资助金额:
    $ 29.63万
  • 项目类别:
MECHANISMS OF ERYTHROCYTIC INFECTIONS AND ANEMIA: NHP MODEL MALARIAL ANEMIA
红细胞感染和贫血的机制:NHP 模型疟疾贫血
  • 批准号:
    7349291
  • 财政年份:
    2006
  • 资助金额:
    $ 29.63万
  • 项目类别:
Mechanisms of Erythrocytic Infection & Anemia in Malaria
红细胞感染的机制
  • 批准号:
    7282022
  • 财政年份:
    2005
  • 资助金额:
    $ 29.63万
  • 项目类别:
Erythrocyte Raft Signaling In Malarial Infection
疟疾感染中的红细胞筏信号传导
  • 批准号:
    7173331
  • 财政年份:
    2005
  • 资助金额:
    $ 29.63万
  • 项目类别:

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