CORE--BIOSTATISTICS AND DATA MANAGEMENT

核心C是这个PPG的新核心。以前，通过核心A（行政核心）向PPG调查员提供统计相关服务。核心C现在是一个独立的核心，由于对这种服务的需求增加。核心C将主要侧重于生物统计和数据管理（BDM），包括测量。然而，核心C还包括“建模”和图像分析的分析组件。我们的目标是确保从一开始就将适当的统计专业知识融入每个项目（例如，设计，功率分析），到实现（例如，测量评估），完成（统计分析，解释和报告）。Core C将提供以下服务：1. 协助设计研究报告。BDM团队的一个主要目标是使研究者在开始他们的主要项目或新的子项目之前获得关于实验设计的建议。2.管理PPG生成的所有数据的电子数据库，确保安全存储和备份，输入的质量和准确性，并及时提供数据文件用于后续分析。3.与研究者和核心人员合作，评价和维护PPG中使用的测量值的可靠性和有效性。4. 协助识别，获取和使用统计分析和相关任务的软件。5. 就调查人员选择进行的统计程序的选择、实施和解释进行咨询。6. 根据需要进行更复杂的统计分析（例如模拟研究、混合模型）。7.合作编写统计和相关方面的文稿。8.促进建模和图像分析程序专业知识的更大发展和使用。八位科学家，包括五位博士。统计员-数据分析员将通过核心C提供支助。通过依靠具有不同专业领域的统计数据分析师团队，我们可以支持几乎任何统计分析领域的项目。

Core C is a new core to this PPG. Previously, statistically related services were offered to PPG investigators through Core A, the administrative core. Core C is now an independent core, due to increased demand for such services. Core C will focus primarily on biostatistics and data management (BDM) including measurement. However, Core C also incorporates analytical components of "modeling" and image analysis. Our objective is to insurer that appropriate statistical expertise is integrated into each project from inception (e.g., design, power analysis), to implementation (e.g., measurement evaluation), to completion (statistical analysis, interpretation, and reporting). Core C will provide the following services: 1. Assistance in the design of studies. A major goal of the BDM team is to enable investigators to obtain advise on experimental design before they begin their primary projects or new sub-projects. 2. Management of an electronic database of all PPG-generated data, ensuring secure storage and back up, quality and accuracy of entry, and timely provision of data files for subsequent analyses. 3. Collaboration with investigators and Core in evaluating and maintaining the reliability and validity of measured used in the PPG. 4. Assistance in identifying, obtaining, and using software for statistical analysis and related tasks. 5. Consultation on the choice, implementation, and interpretation of statistical procedures that investigators choose to conduct themselves. 6. Conduct of more complex statistical analyses as needed (e.g. simulation studies, mixed models). 7. Collaboration on preparing statistical and related aspects of manuscripts. 8. Fostering greater development and use of expertise in modeling and image analysis procedures. Eight scientists including five Ph.D. statistician-data analysts will provide support through Core C. By relying on a team of statistician-data analysts with diverse areas of specialization, we can support the projects in virtually any area of statistical analysis.