CORE--X RAY CRYSTALLOGRAPHY

核心--X射线晶体学

• 批准号: 6605449
• 负责人: Lawrence J Delucas
• 金额: $ 19.59万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-02 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6605449
• 关键词: X ray crystallography; bioimaging /biomedical imaging; biomedical equipment resource; biomedical facility; biomedical resource; chemical models; computer data analysis; computer graphics /printing; computer simulation; molecular oncology; protein structure function; structural biology

Description: (Applicant's Description) The X-ray Crystallography has had a long history as an important research element of the Cancer Center. It provides state-of-the-art x-ray diffraction instrumentation (four Rigaku rotating anode x-ray generators, three Siemans Multiwire area detectors, one MacScience diffraction image processor, a Rigaku R-axis IIc, and a Rigaku R-axis IV) and computer/graphics (SGI Power Onyx, two SGI Maximum Impact graphic stations, a new Origin 2000 compute server and a DEC Alpha 2200 server). The facility supports the work of seven Cancer Center crystallographers who have multiple collaborations with Cancer Center faculty in other programs. The facility provided computer/graphics support to 51 faculty in 8 programs this past year. The facility is housed in 6,500 NASF of Cancer Center space as well as a 1,200 NASF "virtual" theater for Power Onyx-linked large screen three-dimensional stereo projection. The facility is an integral component of the Cancer Center's Structural Biology Program with an emphasis on structure: function relationships, molecular modeling and drug design.

描述：（申请人的描述）X射线晶体学有一个 长期历史是癌症中心的重要研究元素。它 提供最先进的X射线衍射仪器（四个Rigaku 旋转阳极X射线发生器，三个西曼人多线区域探测器，一个 MacScience衍射图像处理器，Rigaku R轴IIC和Rigaku R轴IV）和计算机/图形（SGI Power Onyx，两个SGI最大影响 图形站，新的Origin 2000计算服务器和DEC Alpha 2200 服务器）。该设施支持七个癌症中心的工作 与癌症中心教职员工进行了多次合作的晶体学家 在其他程序中。该设施为51提供了计算机/图形支持 过去一年中的8个课程中的教职员工。该设施位于6,500 NASF中 癌症中心空间以及1,200 NASF“虚拟”剧院 Onyx连接的大屏幕三维立体投影。设施是 癌症中心结构生物学计划的组成部分与 强调结构：功能关系，分子建模和药物 设计。