FAMILY BASED VERSUS ADOLESCENT RESIDENTIAL DRUG TREATMENT

基于家庭的药物治疗与青少年住宅药物治疗

• 批准号: 6618879
• 负责人: Howard Arthur Liddle
• 金额: $ 16.54万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-03-01 至 2004-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6618879
• 关键词: adolescence (12-20); behavioral /social science research tag; clinical research; drug abuse therapy; family therapy; health care cost /financing; human subject; human therapy evaluation; residential care facility

During the past several years, statistics from national samples of high school youth indicate alarming increases in rates of substance use. The primary aims of the proposed study are to: 1) experimentally compare the effectiveness of family-based treatment, Multidimensional Family Therapy (MDFT), with adolescent residential treatment, Adolescent Treatment Program (ATP), in ameliorating drug use and symptoms of co-morbidity among dually diagnosed adolescents; 2) identify the mechanisms by which each treatment achieves its effects; and 3) examine the cost effectiveness and cost off-set of each treatment. ATP is a multifaceted residential treatment based on a social learning approach. MDFT is a multidimensional and intensive, in-home family-based treatment that targets individual, familial, peer, and community influences on drug use. An experimental design is achieved by randomly assigning 200 dually diagnosed adolescents to 2 treatments (MDFT, ATP). Comprehensive assessments of outcome (drug abuse, conduct problems/delinquency, and psychosocial functioning) and change mechanisms (parenting, alliance, 12 step, and adolescent skills) are obtained at 6 time points (intake; 2, 4, 12, 18 months post-intake and termination). Measures of cost effectiveness and cost off-set are included as well as careful procedures for treatment integrity and its measurement. Analyses will include Hierarchical Linear Modeling, Structural Equation Modeling, Multiple Regression, and MANOVA, and utilize latent factor scores representing multiple perspectives on multiple traits.

近几年来，国家样本统计数据显示， 学生的药物使用率出现惊人的增长。这 拟议研究的主要目的是：1）通过实验比较 家庭治疗的有效性，多维家庭治疗 (MDFT)，青少年住院治疗、青少年治疗 计划（ATP），旨在改善药物使用和共病症状 双重诊断青少年； 2) 确定每个机制 治疗达到效果； 3) 检查成本效益 每次治疗的成本抵消。 ATP是一个多方面的住宅 基于社会学习方法的治疗。 MDFT是多维的 以家庭为基础的强化治疗，针对个人、 家庭、同伴和社区对吸毒的影响。 实验设计是通过随机分配 200 个对偶来实现的 诊断青少年接受 2 种治疗（MDFT、ATP）。综合的 结果评估（药物滥用、行为问题/犯罪以及 心理社会功能）和变革机制（养育、联盟、12 步骤和青少年技能）在 6 个时间点（摄入；2、4、 12、摄入和终止后 18 个月）。成本效益衡量标准 包括费用抵消以及仔细的治疗程序 完整性及其测量。分析将包括层次线性 建模、结构方程建模、多元回归和多元方差分析， 并利用代表多个观点的潜在因素得分 多重特质。