Dental Casting of Titanium Alloys

钛合金牙科铸件

• 批准号: 6434128
• 负责人: TORU OKABE
• 金额: $ 27.21万
• 依托单位: TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-05-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6434128
• 关键词: X ray crystallography; alloys; aluminum; biomaterial compatibility; biomaterial development /preparation; biomaterial evaluation; biomechanics; cobalt; corrosions; cytotoxicity; dental bonding material; dental casting material; dental prosthesis; enzyme activity; fiber optic microscopy; fibroblasts; hardness; physical property; porcelain; radiography; succinate dehydrogenase; tensile strength; tissue /cell culture; titanium; transmission electron microscopy

Titanium offers an ideal advantage for biomedical and dental applications: it is nontoxic to humans. Dentistry has lagged behind medicine in practical applications of titanium. The motivation behind the previous and the proposed studies is to learn more about this metal in order to develop its full potential for dentistry. In the previous grant period (1996- 2000), we performed studies on several aspects of dental titanium casting and gained a great deal of knowledge on the casting process itself, on the experimental alloys showing promise for dentistry, and on methods of producing castings that will be acceptable for dental prostheses. The initial project period laid the groundwork for further study in all areas; this renewal proposal is a logical progression of this research program. We propose to refine what we have already learned by expanding our study to ternary and multicomponent alloys. We will study high alloy titanium (greater than 5 percent alloying elements), low alloy titanium (less than 5 percent alloying elements), and titanium intermetallic compounds. Our general hypothesis is that these refined alloy systems will produce properties equaling and possibly surpassing those of presently used dental casting alloys. Additional testing will provide more knowledge in ancillary areas, such as in reducing the reaction of the molten metal to the investment material through face-coating the mold. In addition to tensile fatigue evaluation, fracture toughness and fatigue resistance will be examined using a notchless triangular prism fracture toughness test. Mold filling will be examined by finite element modeling to predict void occurrence. Bond strength of the alloys to porcelain will be analyzed with 3-D finite element modeling. Selected alloys will be examined for cytotoxicity with typical testing methods. The specific aims to be addressed are: 1) to evaluate the proposed experimental binary, ternary, and multicomponent alloys (including intermetallics) for mechanical properties pertinent to the requirements for dental applications; 2) to examine the quality of the cast experimental alloys based on the requirements for acceptable dental prostheses in the areas of mold filling, casting accuracy, and subsurface structures; 3) to evaluate the corrosion behavior and biocompatibility of the experimental alloys; 4) to examine the characteristics of cast experimental alloys necessary for dental applications, including bond strength to porcelain, machinability, and wear behavior; and 5) to evaluate the fatigue resistance and fracture toughness of the experimental cast alloys.

钛为生物医学和牙科应用提供了理想的优势：它对人类无毒。 牙科在钛的实际应用方面落后于医学。先前和拟议研究背后的动机是更多地了解这种金属，以充分发挥其在牙科领域的潜力。 在上一个资助期（1996 - 2000年），我们对牙科钛铸造的几个方面进行了研究，并获得了大量关于铸造工艺本身的知识，展示牙科前景的实验合金，以及生产可用于牙科修复体的铸件的方法。 最初的项目期为所有领域的进一步研究奠定了基础;这一更新建议是该研究计划的一个合乎逻辑的进展。 我们建议通过将我们的研究扩展到三元和多元合金来完善我们已经学到的知识。 我们将研究高合金钛（大于5%的合金元素），低合金钛（小于5%的合金元素）和钛金属间化合物。 我们的一般假设是，这些精炼合金系统将产生等于或可能超过目前使用的牙科铸造合金的性能。 额外的测试将提供更多的知识，在辅助领域，如在减少反应的熔融金属的投资材料，通过表面涂层的模具。除了拉伸疲劳评价外，还将使用无缺口三棱柱断裂韧性试验检查断裂韧性和抗疲劳性。 将通过有限元建模检查模具填充，以预测空隙的发生。 将用三维有限元模型分析合金与瓷的结合强度。 将采用典型试验方法检查选定合金的细胞毒性。 具体的目标是：1）评估所提出的实验二元，三元和多元合金（包括金属间化合物）用于与牙科应用的要求相关的机械性能; 2）基于在模具填充、铸造精度和表面下结构方面可接受的牙科假体的要求来检查铸造实验合金的质量; 3）评估实验合金的腐蚀行为和生物相容性; 4）检查牙科应用所需的铸造实验合金的特性，包括与瓷的结合强度、可加工性和磨损行为;和5）评估实验铸造合金的抗疲劳性和断裂韧性。