Study of Viral Resistance to Antiviral Therapy of Chron*

Chron 抗病毒治疗的病毒耐药性研究*

• 批准号: 6647700
• 负责人: Steven H. Belle
• 金额: $ 170万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-01 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6647700
• 关键词: African American; caucasian American; chronic disease /disorder; clinical trials; computer data analysis; cooperative study; data management; drug resistance; experimental designs; genetic susceptibility; hepatitis C; human data; information systems; interferon alpha; liver disorder chemotherapy; patient oriented research; racial /ethnic difference; ribavirin; virus genetics

The Data Coordinating Center (DCC) will collaborate with Clinical Centers, ancillary study sites, central laboratories and pathologist, and the National Institute of Diabetes and Digestive and Kidney Diseases project scientist to design and carry out the "Study of viral resistance to antiviral therapy of chronic hepatitis C." The DCC brings together substantive, methodological, analytic and managerial expertise from the University of Pittsburgh Graduate School of Public Health. The DCC will: a. Identify and compile background information regarding diagnosis and treatment for patients with hepatitis C infection b. In collaboration with other investigators, develop the study protocol c. Provide training and develop quality control procedures to assure consistent protocol implementation d. Develop computerized database e. Monitor ongoing progress of study f. Collect, edit, store, and manage data g. Analyze data and report study results h. Provide administrative support

数据协调中心（DCC）将与临床中心、辅助研究中心、中心实验室和病理学家以及国家糖尿病、消化和肾脏疾病研究所的项目科学家合作，设计和开展“慢性丙型肝炎抗病毒治疗的病毒耐药性研究”。 DCC 汇集了匹兹堡大学公共卫生研究生院的实质性、方法论、分析和管理专业知识。 DCC 将：确定并汇编有关丙型肝炎感染患者诊断和治疗的背景信息 b．与其他研究人员合作，制定研究方案 c．提供培训并制定质量控制程序，以确保一致的方案实施 d．开发计算机化数据库 e. f. 监控研究的持续进展。收集、编辑、存储和管理数据 g．分析数据并报告研究结果 h．提供行政支持