Continuation of the Longitudinal Assessment of Bariatric Surgery (LABS) - DCC

减肥手术纵向评估 (LABS) 的延续 - DCC

基本信息

  • 批准号:
    8011285
  • 负责人:
  • 金额:
    $ 77.25万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2010
  • 资助国家:
    美国
  • 起止时间:
    2010-03-15 至 2012-02-28
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): LABS was conceived to address important issues in bariatric surgery and metabolism in adults, exploring relationships of patient characteristics, clinical conditions, serologic and genetic markers, and clinical, psychosocial and health economic outcomes. The primary achievements of LABS have been establishing a research consortium and its infrastructure; defining domains of exploration, specific research questions and an effective study design to efficiently address those questions; identifying appropriate metrics; designing and implementing a web-based data collection system and an extensive database; completing a cohort of over 5000 participants to study the short-term safety of bariatric surgery; enrolling approximately 2000 participants into a 2400 person cohort intended to address longer term safety and efficacy; and implementing 2 substudies. The Data Coordinating Center (DCC) provides logistical and administrative support and expertise in database management, website construction and maintenance, computer systems, epidemiology, biostatistics, and methodology. During this proposed continuation of LABS, the DCC will continue to support the consortium in all aspects of study design, conduct, analysis, logistics, and administration. This includes maintaining the distributed data entry and database management systems; maintaining contact with the NIDDK-supported biospecimen and data repositories; administering a subcontract with a Central Laboratory if necessary; assisting the study pathologist with respect to biopsy specimen tracking and data collection; maintaining and improving the study website that has public, private, participant and systems areas; providing logistical support to the Clinical Centers, NIDDK Project Scientist, committees and subcommittees, central facilities, and Data and Safety Monitoring Board (DSMB); and analyzing and reporting study results to better inform the research and public communities regarding long-term outcomes following bariatric surgery. Obesity is a major public health problem expected to increase in the future. Bariatric surgery is currently the most effective long term therapy. This multi-center consortium was created to "facilitate coordinated clinical, epidemiological, and behavioral research in...bariatric surgery". The data coordinating center provides logistical and scientific support, and developed the core database.
描述(由申请人提供): LABS旨在解决成人减肥手术和代谢中的重要问题,探索患者特征,临床状况,血清学和遗传标记物以及临床,心理社会和健康经济结果之间的关系。LABS的主要成就是建立了一个研究联盟及其基础设施;定义了探索领域,具体的研究问题和有效的研究设计,以有效地解决这些问题;确定适当的指标;设计和实施基于网络的数据收集系统和广泛的数据库;完成了一个超过5000名参与者的队列研究减肥手术的短期安全性;将约2000名受试者纳入2400人队列,旨在研究长期安全性和有效性;并实施2项子研究。数据协调中心(DCC)提供数据库管理、网站建设和维护、计算机系统、流行病学、生物统计学和方法学方面的后勤和行政支持以及专业知识。在拟议的LABS延续期间,DCC将继续在研究设计、实施、分析、后勤和管理的各个方面为联合体提供支持。这包括维护分布式数据输入和数据库管理系统;与NIDDK支持的生物标本和数据储存库保持联系;必要时与中心实验室管理活检;协助研究病理学家进行活检标本跟踪和数据收集;维护和改进研究网站,包括公共、私人、参与者和系统区域;为临床中心、NIDDK项目科学家、委员会和小组委员会、中心设施以及数据和安全监测委员会(DSMB)提供后勤支持;分析和报告研究结果,以更好地告知研究和公众社区减肥手术后的长期结果。 肥胖是一个主要的公共卫生问题,预计在未来会增加。减肥手术是目前最有效的长期治疗方法。这个多中心联盟的创建是为了“促进协调的临床,流行病学和行为研究......减肥手术”。数据协调中心提供后勤和科学支持,并开发了核心数据库。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Steven H. Belle其他文献

Su1336: TREATMENT INITIATION AND OUTCOMES OF AFRICAN AMERICANS AND NON-AFRICAN AMERICANS WITH CHRONIC HEPATITIS B VIRUS (HBV) INFECTION
  • DOI:
    10.1016/s0016-5085(22)63528-5
  • 发表时间:
    2022-05-01
  • 期刊:
  • 影响因子:
  • 作者:
    Mohamed Hassan;Kelsey R. Leonard;Marc G. Ghany;Mandana Khalili;Lewis R. Roberts;Richard K. Sterling;Steven H. Belle;Anna Lok
  • 通讯作者:
    Anna Lok
AH-07: Physical activity levels of patients undergoing bariatric surgery in the longitudinal assessment of bariatric surgery (LABS) study
  • DOI:
    10.1016/j.soard.2008.03.025
  • 发表时间:
    2008-05-01
  • 期刊:
  • 影响因子:
  • 作者:
    Wendy C. King;Steven H. Belle;William H. Chapman;Anita P. Courcoulas;Gregory Dakin;George M. Eid;David R. Flum;William B. Inabnet;James Mitchell;Brant Oelschlager;Emma J. Patterson;Bruce M. Wolfe
  • 通讯作者:
    Bruce M. Wolfe
Familial influences on breast parenchymal patterns
家族对乳腺实质模式的影响
  • DOI:
  • 发表时间:
    1980
  • 期刊:
  • 影响因子:
    6.2
  • 作者:
    J. Wolfe;S. Albert;Steven H. Belle;M. Salane
  • 通讯作者:
    M. Salane
P-69 Explaining the volume outcome relationship in bariatric surgery
  • DOI:
    10.1016/j.soard.2011.04.071
  • 发表时间:
    2011-05-01
  • 期刊:
  • 影响因子:
  • 作者:
    Mark D. Smith;Abdus Wahed;Bruce M. Wolfe;Emma J. Patterson;Steven H. Belle;Anita P. Courcoulas;Surebh Khandelwal;David R. Flum;James E. Mitchell;Alfons Pomp;Walter J. Pories
  • 通讯作者:
    Walter J. Pories
Report from the Pitt-UNOS Liver Transplant Registry.
来自 Pitt-UNOS 肝移植登记处的报告。
  • DOI:
  • 发表时间:
    1993
  • 期刊:
  • 影响因子:
    0.9
  • 作者:
    Steven H. Belle;K. Detre
  • 通讯作者:
    K. Detre

Steven H. Belle的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Steven H. Belle', 18)}}的其他基金

The Physiology of the Weight Reduced State Data Coordinating Center
减肥的生理学状态数据协调中心
  • 批准号:
    10395562
  • 财政年份:
    2021
  • 资助金额:
    $ 77.25万
  • 项目类别:
The Physiology of the Weight Reduced State Data Coordinating Center
减肥的生理学状态数据协调中心
  • 批准号:
    10188159
  • 财政年份:
    2021
  • 资助金额:
    $ 77.25万
  • 项目类别:
The Physiology of the Weight Reduced State Data Coordinating Center
减肥的生理学状态数据协调中心
  • 批准号:
    10612227
  • 财政年份:
    2021
  • 资助金额:
    $ 77.25万
  • 项目类别:
The Physiology of the Weight Reduced State Data Coordinating Center
减肥的生理学状态数据协调中心
  • 批准号:
    10618137
  • 财政年份:
    2021
  • 资助金额:
    $ 77.25万
  • 项目类别:
Data Management and Statistical Core
数据管理与统计核心
  • 批准号:
    10410383
  • 财政年份:
    2020
  • 资助金额:
    $ 77.25万
  • 项目类别:
Data Management and Statistical Core
数据管理与统计核心
  • 批准号:
    10590699
  • 财政年份:
    2020
  • 资助金额:
    $ 77.25万
  • 项目类别:
Data Management and Statistical Core
数据管理与统计核心
  • 批准号:
    10161688
  • 财政年份:
    2020
  • 资助金额:
    $ 77.25万
  • 项目类别:
Cross-study analysis of coordinated randomized clinical trials for weight managem
体重管理协调随机临床试验的交叉研究分析
  • 批准号:
    8969694
  • 财政年份:
    2014
  • 资助金额:
    $ 77.25万
  • 项目类别:
Cross-study analysis of coordinated randomized clinical trials for weight managem
体重管理协调随机临床试验的交叉研究分析
  • 批准号:
    8790798
  • 财政年份:
    2014
  • 资助金额:
    $ 77.25万
  • 项目类别:
Enhanced Behavioral Intervention to Improve Long-Term Weight Loss in Young Adults
加强行为干预以改善年轻人的长期减肥效果
  • 批准号:
    7919261
  • 财政年份:
    2009
  • 资助金额:
    $ 77.25万
  • 项目类别:

相似海外基金

Rational design of rapidly translatable, highly antigenic and novel recombinant immunogens to address deficiencies of current snakebite treatments
合理设计可快速翻译、高抗原性和新型重组免疫原,以解决当前蛇咬伤治疗的缺陷
  • 批准号:
    MR/S03398X/2
  • 财政年份:
    2024
  • 资助金额:
    $ 77.25万
  • 项目类别:
    Fellowship
CAREER: FEAST (Food Ecosystems And circularity for Sustainable Transformation) framework to address Hidden Hunger
职业:FEAST(食品生态系统和可持续转型循环)框架解决隐性饥饿
  • 批准号:
    2338423
  • 财政年份:
    2024
  • 资助金额:
    $ 77.25万
  • 项目类别:
    Continuing Grant
Re-thinking drug nanocrystals as highly loaded vectors to address key unmet therapeutic challenges
重新思考药物纳米晶体作为高负载载体以解决关键的未满足的治疗挑战
  • 批准号:
    EP/Y001486/1
  • 财政年份:
    2024
  • 资助金额:
    $ 77.25万
  • 项目类别:
    Research Grant
Metrology to address ion suppression in multimodal mass spectrometry imaging with application in oncology
计量学解决多模态质谱成像中的离子抑制问题及其在肿瘤学中的应用
  • 批准号:
    MR/X03657X/1
  • 财政年份:
    2024
  • 资助金额:
    $ 77.25万
  • 项目类别:
    Fellowship
CRII: SHF: A Novel Address Translation Architecture for Virtualized Clouds
CRII:SHF:一种用于虚拟化云的新型地址转换架构
  • 批准号:
    2348066
  • 财政年份:
    2024
  • 资助金额:
    $ 77.25万
  • 项目类别:
    Standard Grant
The Abundance Project: Enhancing Cultural & Green Inclusion in Social Prescribing in Southwest London to Address Ethnic Inequalities in Mental Health
丰富项目:增强文化
  • 批准号:
    AH/Z505481/1
  • 财政年份:
    2024
  • 资助金额:
    $ 77.25万
  • 项目类别:
    Research Grant
ERAMET - Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
ERAMET - 快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
  • 批准号:
    10107647
  • 财政年份:
    2024
  • 资助金额:
    $ 77.25万
  • 项目类别:
    EU-Funded
BIORETS: Convergence Research Experiences for Teachers in Synthetic and Systems Biology to Address Challenges in Food, Health, Energy, and Environment
BIORETS:合成和系统生物学教师的融合研究经验,以应对食品、健康、能源和环境方面的挑战
  • 批准号:
    2341402
  • 财政年份:
    2024
  • 资助金额:
    $ 77.25万
  • 项目类别:
    Standard Grant
Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
  • 批准号:
    10106221
  • 财政年份:
    2024
  • 资助金额:
    $ 77.25万
  • 项目类别:
    EU-Funded
Recite: Building Research by Communities to Address Inequities through Expression
背诵:社区开展研究,通过表达解决不平等问题
  • 批准号:
    AH/Z505341/1
  • 财政年份:
    2024
  • 资助金额:
    $ 77.25万
  • 项目类别:
    Research Grant
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了