Enhanced Behavioral Intervention to Improve Long-Term Weight Loss in Young Adults

加强行为干预以改善年轻人的长期减肥效果

• 批准号: 7919261
• 负责人: Steven H. Belle
• 金额: $ 114.35万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-20 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7919261
• 关键词: Achievement; Address; Adherence; Age-Years; Behavior Therapy; Behavioral; Body Composition; Body Weight; Body Weight decreased; Body fat; Cardiovascular Diseases; Chronic; Development; Diabetes Mellitus; Dietary intake; Energy Intake; Energy Metabolism; Enhancement Technology; Evaluation; Exercise; Feedback; Goals; Individual; Instruction; Intervention; Intervention Studies; Link; Malignant Neoplasms; Measures; Methods; Monitor; Motivation; Musculoskeletal; Obesity; Outcome; Overweight; Physical activity; Physiological; Prevalence; Public Health; Randomized; Self Efficacy; Technology; Text; Time; Weight; Weight maintenance regimen; abstracting; age group; behavior change; effective intervention; expectation; fitness; improved; programs; psychosocial; response; weight loss intervention; young adult

DESCRIPTION (provided by applicant): This application is in response to RFA-HL-08-007 "Targeted Approaches to Weight Control for Young Adults". As outlined in the RFA, this application will focus on development, refinement, and evaluation of a behavioral approach to weight control in young adults, with the focus of this application being on enhancing long-term weight loss. Consistent with the RFA, young adults for this application are defined as individuals 18-35 years of age. The prevalence of obesity in young adults has been increasing, and excessive body weight have been linked to numerous chronic conditions including cardiovascular disease, diabetes, many forms of cancer, and numerous musculoskeletal problems. The focus of this application is to develop and evaluate interventions that may be appropriate for young adults to improve weight loss outcomes following a 24 month intervention. Therefore, the primary aim of this study is to examine whether an enhanced weight loss intervention (EWLI) that includes technology components results in improved weight loss in young adults (18-35 years of age) compared to a standard behavioral weight loss intervention (SBWP) over a period of 24 months. Additional aims include examination of these interventions on changes in body composition, body fat distribution, fitness, physical activity, dietary intake, and behavioral/psychosocial measures that may be predictive of behavior change. Assessments will occur at 0, 6, 12,18, and 24 months. This study involves the recruitment of 480 overweight and obese young adults (18-35 years of age). Subjects will participate in a 24 month behavioral weight loss program that includes a reduction in energy ntake and moderate-to-vigorous intensity exercise (progressively increasing from 100 to 300 minutes per week). Subjects will be randomized to receive this intervention (SBWP) or this intervention in combination with technology enhancements (EWLI). EWLI will receive daily text messaging prompts to reinforce adherence to the behavioral intervention from months 7-24, and will wear a monitor from months 13-24 that provides real-time feedback on energy expenditure and achievement of daily physical activity goals. It is hypothesized that these technology enhancements to EWLI will significantly improve weight loss, body composition, body fat distribution, fitness, physical activity, and dietary intake compared to SBWP. RELEVANCE (See instructions): Obesity rates of young adults have significantly increased and the ability to sustain weight loss long-term in this age group has been less than desirable. Therefore, there is a need to develop and implement effective intervention initiatives to address this public health concern, which is the focus of this proposed intervention study. (End of Abstract)

描述(申请人提供)：本申请是对RFA-HL-08-007《针对青少年体重控制的针对性方法》的回应。正如RFA中概述的那样，该应用程序将专注于开发、改进和评估年轻人体重控制的行为方法，该应用程序的重点是促进长期减肥。与RFA一致，适用于这一申请的年轻人被定义为18-35岁的个人。年轻人的肥胖率一直在上升，超重与许多慢性疾病有关，包括心血管疾病、糖尿病、多种形式的癌症和许多肌肉骨骼问题。这项应用的重点是开发和评估可能适合年轻人的干预措施，以改善干预24个月后的减肥结果。因此，这项研究的主要目的是检验在24个月的时间里，与标准行为减肥干预(SBWP)相比，包括技术成分的增强型减肥干预(EWLI)是否能改善年轻人(18-35岁)的减肥效果。其他目标包括检查这些关于身体成分、体脂分布、健身、体力活动、饮食摄入量变化的干预措施，以及可能预测行为变化的行为/心理社会指标。评估将在0、6、12、18和24个月进行。这项研究涉及招募480名超重和肥胖的年轻人(18-35岁)。受试者将参加为期24个月的行为减肥计划，其中包括减少能量摄入和中等到剧烈强度的运动(从每周100分钟逐渐增加到300分钟)。受试者将随机接受这种干预(SBWP)或这种结合技术增强的干预(EWLI)。EWLI将在7-24个月每天收到短信提示，以加强对行为干预的遵守，并将在13-24个月佩戴监测器，提供有关能量消耗和每日体力活动目标实现情况的实时反馈。据推测，与SBWP相比，EWLI的这些技术改进将显著改善体重减轻、身体成分、体脂分布、健身、体力活动和饮食摄入量。相关性(见说明)：年轻人的肥胖率显著增加，这一年龄段长期保持减肥的能力并不令人满意。因此，有必要制定和实施有效的干预措施来解决这一公共卫生问题，这也是这项拟议干预研究的重点。(摘要结束)