课题基金 / 基金详情

CORE--MOLECULAR BIOLOGY AND MONOCLONAL ANTIBODY

CORE--MOLECULAR BIOLOGY AND MONOCLONAL ANTIBODY
核心--分子生物学与单克隆抗体
批准号：
6809831
负责人：
Wanda K O'Neal
金额：
$14.86万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
项目状态：
已结题
起止时间：
2003-09-16 至 2008-08-31
来源：
https://reporter.nih.gov/project-details/6809831
关键词：
biological models biomedical facility biotechnology cystic fibrosis enzyme linked immunosorbent assay flow cytometry genetically modified animals genotype immunologic substance development /preparation laboratory mouse model design /development molecular biology monoclonal antibody polymerase chain reaction proteomics reagent /indicator tissue /cell culture transfection /expression vector

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中文摘要
翻译
分子/抗体核心实验室将为SCOR应用程序中的项目和其他核心所需的分子和单抗试剂和服务的开发提供集中设施。谨慎的做法是将与分子生物学相关的实验和抗体生产集中在一个中心位置/管理单位。这一战略将有效地利用项目本身的人员时间，将研究人员从载体构建、转基因动物开发和基因分型以及抗体开发和表征的负担中解脱出来，从而使他们能够专注于使用产生的实验试剂进行重点生理和生物学研究。
英文摘要
The Molecular/Antibody Core Laboratory will provide centralized facilities for development of molecular and monoclonal antibody reagents and services as required for the projects and other cores within the SCOR application. It is prudent to centralize molecular biology related experiments and antibody production into one central location/administrative unit. This strategy will provide efficient use of personnel time within the projects themselves, ridding investigators of the burdens of vector construction, transgenic animal development and genotyping, and antibody development and characterization, thus allowing them to focus on the use of the generated experimental reagents for focused physiological and biological studies.
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