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Core D- Electrophysiology Core

Core D- Electrophysiology Core
核心 D- 电生理学核心
批准号：
6823467
负责人：
Elda Arrigoni
金额：
$9.86万
依托单位：
BRIGHAM AND WOMEN'S HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
项目状态：
已结题
起止时间：
2003-09-08 至 2008-08-31
来源：
https://reporter.nih.gov/project-details/6823467
关键词：
biomedical facility electronic recording system electrophysiology evoked potentials hippocampus laboratory mouse laboratory rat long term potentiation neuroimaging preoptic areas prosencephalon sleep apnea voltage /patch clamp

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中文摘要
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英文摘要
The Electrophysiology Core will provide centralized services for in vitro electrophysiological studies, including preparation of the in vitro brain slices, patch-clamp recordings, extracellular recordings, and the associated image and data processing plus analysis. Five aims in four projects will utilize this Core facility. Whole-cell patch-clamp recordings will be obtained from in vitro rat brain slices from basal forebrain neurons (Projects 2 & 3), ventrolateral preoptic (VLPO) neurons (Project 3) and from mouse tuberornarnmUlary, locus coeruleus and basal forebrain neurons (Project 5). In addition, extracellular recordings of hippocampal field potentials will be obtained from the CA1 region (Projects 2 & 4). The centralization of this resource makes the technique of in vitro electrophysiological recording available to multiple investigators in an environment that facilitates standardization of recording conditions across all projects.
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Neuronal circuit controlling sleep-promoting ventrolateral preoptic neurons
Neuronal Circuit Controlling Sleep-Promoting Ventrolateral Preoptic Neurons
Core C
Core C