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Core C- Behavioral Core

Core C- Behavioral Core
核心C-行为核心
批准号：
6823465
负责人：
Mark G Baxter
金额：
$11.8万
依托单位：
BRIGHAM AND WOMEN'S HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
项目状态：
已结题
起止时间：
2003-09-08 至 2008-08-31
来源：
https://reporter.nih.gov/project-details/6823465
关键词：
attention behavior test biomedical facility laboratory mouse laboratory rat learning memory neuropsychological tests psychomotor function sleep sleep apnea space perception

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英文摘要
The Behavioral Core (Core C) will perform behavioral analyses of rats and mice from three projects (Projects 2, 4, and 5) of the SCOR. Sleep apnea and sleep disruption cause cognitive impairments in humans. The Behavioral Core will examine the consequences of physiological and sleep manipulations on cognitive function in rats (Projects 2 and 4) and mice (Project 5). The tasks we use will test motor skills, spatial learning and memory, paired-associate learning, attention/vigilance, and working memory/executive function. As a Specific Aim of Core C we will develop and validate a modified version of a standard attentional task (the 5-choice serial reaction time task) as a test of vigilance and wakefulness in rats and mice.
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