Research Training in the Neuroscience of Aging

项目摘要 老年神经科学研究培训计划为神经科学博士前学生提供 在国内和国际公认的教师的实验室中拥有综合培训经验。这个 博士前培训计划建立在一年级和一年级教授的令人兴奋的、与翻译相关的课程基础上 两名研究生通过联合赞助的博士前早期获得了NIH的支持 阶段T32培训计划机制(T32 MH087004)。这是西奈山第一个 特别关注衰老和与年龄相关的神经退行性疾病的神经科学(主要是 阿尔茨海默病)，补充了西奈山在这些方面的历史专注和研究实力 区域。在这个项目中，优秀的培训人员在大脑机制方面有着共同的研究兴趣。 在健康和疾病中发挥作用，采用各种实验方法，并在 分析范围从分子神经生物学到人类神经心理学和神经成像。培训 该计划特别鼓励教师导师的参与，他们的研究拨款直接侧重于老龄化问题。 神经科学研究，但不排除那些研究专长对 我们寻求传授跨学科的培训。通过他们的课程学习，博士后实习生将获得 扎实的神经生物学基础，以及神经和精神疾病的病理生理学 作为生物统计学和负责任的研究行为。高级课程包括两门研讨会课程， 一个关于衰老的生物学，一个关于衰老的神经科学，补充了广泛的基础知识 神经科学方面的课程。研究导师的选择是在一个积极主动的合作环境中进行的 促进多学科、综合性研究。研究培训也有一个“进行中的工作”部分，以 培养重要的跨学科互动，磨练演讲和写作技能，并提高对 道德问题。该项目于2015年9月开始，有4个博士前培训时段，迄今已 资助了8名学生，其中2名已经参加了博士生培训。使用这种方法，程序 老年神经科学研究培训为博士生提供指导和 我们培训教师的实验室中的实验工具，以启动成功、高效和独立的 从事老龄化研究的职业。

Project Summary The program on Research Training in the Neuroscience of Aging provides predoctoral students in Neuroscience with an integrated training experience in the laboratories of nationally and internationally recognized faculty. The predoctoral training program builds on an exciting, translationally relevant curriculum taught in years one and two of graduate school that has been awarded NIH support through the Jointly Sponsored Predoctoral Early Stage T32 Training Program mechanism (T32 MH087004). This training program is the first at Mount Sinai to focus specifically on the neuroscience of aging and age-related neurodegenerative diseases (primarily Alzheimer's disease), complementing Mount Sinai's historical concentration and strength in research in these areas. Outstanding training faculty in this program share common research interests in the mechanisms of brain function in health and disease, employing a diversity of experimental approaches and working at levels of analysis ranging from molecular neurobiology to human neuropsychology and neuroimaging. The training program specifically encourages participation of faculty mentors whose research grants directly focus on aging neuroscience research, while not excluding those whose research expertise is critically important for the interdisciplinary training we seek to impart. Through their coursework, predoctoral trainees will have received a solid foundation in basic neurobiology and the pathophysiology of neurological and psychiatric diseases, as well as biostatistics and the responsible conduct of research. Advanced coursework includes two seminar courses, one on the biology of aging and one on the neuroscience of aging, complementing the broad foundational coursework in neuroscience. Selection of a research mentor is made in a collaborative environment that actively promotes multidisciplinary, integrative research. Research training also has a ‘work in progress’ component, to foster important interdisciplinary interactions, hone presentation and writing skills, and improve awareness of ethical issues. This program began in September of 2015 with 4 predoctoral training slots and to date has supported 8 students, 2 of whom have already competed their PhD training. Using this approach, the program on Research Training in the Neuroscience of Aging provides predoctoral students with the guidance and experimental tools, in the laboratories of our training faculty, to launch successful, productive, and independent careers in aging research.