Stroke Surveillance in a Biethnic Community

描述（由申请人提供）：在明确了解疾病负担和人群中介导这种疾病的相关因素的情况下，针对公共卫生干预策略的效果最好。我们正在研究的疾病是中风：全国第一大致残原因和第三大死亡原因。我们正在研究的人口是墨西哥裔美国人：他们占西班牙裔美国人的绝大多数，是美国最大的少数民族人口。科珀斯克里斯蒂脑梗塞监测（BASIC）项目于2000年1月在德克萨斯州东南部开始了严格的、以人群为基础的中风监测。研究对象的招募工作已经大大提前了。社区、地方公共卫生部门和调查人员之间的巨大合作，使中风病例得以完全确定，并有详细的程序来确认其诊断。

DESCRIPTION (provided by applicant): Targeting public health intervention strategies proceeds best with a clear understanding of the burden of disease and the associated factors that mediate this disease within a population. The disease that we are studying is stroke: the nation's number one cause of disability and third leading cause of death. The population we are studying is Mexican Americans: the overwhelming largest component of Hispanic Americans, the nation's largest minority population. The Brain Attack Surveillance In Corpus Christi (BASIC) Project began rigorous, population-based stroke surveillance in southeastern Texas in January 2000. Recruitment of study subjects has progressed far ahead of schedule. The tremendous collaboration among community, local Public Health Department and investigators has enabled complete ascertainment of stroke cases and detailed procedures to confirm their diagnosis. The BASIC Project aims to provide information to the scientific and public health community regarding stroke in Mexican Americans in two complementary areas. The first objective is to provide accurate rates of transient ischemic attack, first ever and total ischemic stroke, intercerebral hemorrhage and subarachnoid hemorrhage. The relative burden of these diseases in Mexican Americans and non-Hispanic whites will be determined in the fastidious manner that can only occur in a population-based study. The second aspect of the project is to delve deeply into the relationships of access to care, acculturation, stroke risk factors and social determinants of health as these factors interact with ethnicity in their association with stroke. We are confident that our efforts in these two approaches to health disparities will yield critical information that will form a foundation for scientists in the future to reduce race/ethnic health disparities. The Mexican American population is growing and aging quickly. The physical and emotional burden from stroke to this population will grow exponentially over the next few decades. Consequently, the economic burden for stroke will mount for all taxpayers. The BASIC Project reflects years of planning, pilot work, and now detailed, hands-on experience in fostering community relations, collaboration, data acquisition, and analysis. This project began running right out of the blocks and we are in the middle of our sprint. Renewal of this project for an additional five years will enable us to complete the mission we have begun. We will accomplish this with the highest scientific integrity and provide the rich data that people around the country who have seen our project grow have come to expect.