Brain Attack Surveillance in Durango

描述（由申请人提供）：本研究将主要在墨西哥杜兰戈与卡洛斯坎图博士合作完成，作为NIH资助R 01 NS 38916的扩展。本申请是对PAR-05-072“国际研究合作”的回应。“该项目是一项试点和可行性研究，旨在墨西哥杜兰戈建立一个严格的中风监测系统。随着发展中世界的增长和老龄化，中风等疾病在死亡、残疾和保健支出方面将变得更加重要。建立高质量的监测系统，以确定全球健康差距和评估干预措施的效果，至关重要。该项目源于非常成功的Corpus Christi（BASIC）项目（NIH RO 1 NS 38916）。BASIC在德克萨斯州科珀斯克里斯蒂的一项基于人群的研究中，比较了墨西哥裔美国人和非西班牙裔白人的相对中风健康差异。我们试图在墨西哥杜兰戈建立一个同样严格的基于人群的研究。这项建议的一个关键部分是在墨西哥发展研究基础设施，以促进以人口为基础的研究，这将有助于监测疾病趋势以及这个重要发展中国家公共卫生治疗和预防方案的效果。在这项研究结束时，我们将建立一个框架，正在进行的人口为基础的研究，在一个有代表性的墨西哥社区。我们将与科学调查人员和公共卫生官员广泛合作，建立重要的基础设施，为正在进行的研究奠定框架，以减少全球健康不平等，大大改善我们南部邻国的健康。

DESCRIPTION (provided by applicant): This research will be done primarily in Durango, Mexico in collaboration with Dr. Carlos Cantu as an extension of NIH grant R01 NS38916. This application is in response to PAR-05-072 "International Research Collaboration." This project is a pilot and feasibility study aimed at developing a rigorous stroke surveillance system in Durango, Mexico. As the developing world grows and ages, diseases such as stroke will be even more critically important with respect to death, disability and health care expenditures. High quality monitoring systems to determine global health disparities and assess the effect of interventions are of utmost importance. This project grows out of the highly successful Brain Attack Surveillance in Corpus Christi (BASIC) Project (NIH RO1 NS38916). BASIC has identified the relative stroke health disparity comparing Mexican Americans and non-Hispanic whites in a population-based study in Corpus Christi, Texas. We seek to establish an equally rigorous population-based study in Durango, Mexico. A key part of this proposal is the development of research infrastructure within Mexico to facilitate population- based research that will facilitate monitoring disease trends and the effects of public health treatment and prevention programs within this vital developing country. At the conclusion of this study we will have established the framework for ongoing population-based research in a representative Mexican community. We will have worked extensively with scientific investigators and public health officials to build vital infrastructure that will lay the framework for ongoing studies to reduce global health inequalities and greatly improve the health of our neighbor to the south.