Cognitive impairment in Mexican Americans: a population-based study

墨西哥裔美国人的认知障碍：一项基于人群的研究

• 批准号: 10214705
• 负责人: LEWIS B MORGENSTERN
• 金额: $ 140.61万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-25 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10214705
• 关键词: Address; Adult; Age; Age-Years; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Caregiver Burden; Caregivers; Caring; Cerebrovascular Disorders; Characteristics; Cognition Disorders; Communities; County; Dementia; Epidemiologic Methods; Epidemiology; Ethnic Origin; Family; Family member; Growth; Health; Health and Retirement Study; Health behavior; Hispanics; Impaired cognition; Individual; Intervention; Latino; Lead; Mental Health; Methods; Mexican Americans; Minority Groups; Needs Assessment; Not Hispanic or Latino; Outcome; Patients; Personal Satisfaction; Population; Population Study; Positioning Attribute; Prevalence; Recording of previous events; Reporting; Research; Resources; Risk Factors; Role; Societies; Socioeconomic Status; Stroke; Texas; Time; United States; Vascular Diseases; Work; base; cost; dementia caregiving; ethnic disparity; follow-up; improved; informal caregiver; informal caregiving; member; novel; physical conditioning; population based; resilience

Abstract Hispanic/Latinos will comprise more than 30% of the U.S. population by mid-century, and Mexican Americans account for the largest share of this growing segment of society. This proposal aims to use door-to-door surveillance in Nueces County, Texas, a non-immigrant, bi-ethnic community, to determine the prevalence and trajectory over time of cognitive impairment and dementia in Mexican Americans and non-Hispanic whites. We will elucidate the mechanisms that explain the hypothesized ethnic disparity in Alzheimer’s disease and Alzheimer-related dementias by evaluating the roles of vascular disease risk factors, educational attainment and socio-economic status among others. This research will also delve deeply into the differences in informal caregiving for Mexican American and non-Hispanic whites with cognitive impairment and dementia. Caregiver burden and mental and physical health of caregivers will be examined toward efforts to develop interventions that build resilience in caregivers. A novel ability of this population-based study is to examine community resources for both patients and caregivers, and how these provisions differ by ethnicity. Using a rigorous mixed methods approach we will identify the gap between available resources and needs for those with cognitive impairment and dementia. In this way we will be well positioned to propose ethnic-specific testable interventions that promote mental and physical health for those with cognitive impairment and dementia, as well as for those family members who provide the care. This research will therefore lead to improved well- being, autonomy and outcomes among those with cognitive impairment and dementia and their caregivers. The investigative team members have conducted research in this community for 20 years and are experts in Mexican American culture and health, cognitive impairment and dementia, epidemiologic methods, community needs assessment and health behavior research. As the Mexican American population continues its tremendous growth and aging it is vitally important to better understand the prevalence and outcomes of cognitive impairment and dementia in this population, and to rapidly develop interventions that address the burden of these common conditions in Mexican American adults, families, and communities.

抽象的 到本世纪中叶，西班牙裔/拉丁裔将占美国人口的 30% 以上，墨西哥裔美国人 在这个不断增长的社会群体中占据最大份额。本提案旨在采用挨家挨户的方式 在德克萨斯州纽埃西斯县（一个非移民双族社区）进行监测，以确定患病率和 墨西哥裔美国人和非西班牙裔白人认知障碍和痴呆症随时间的变化轨迹。我们 将阐明解释阿尔茨海默病中假设的种族差异的机制 通过评估血管疾病危险因素、教育程度的作用来治疗阿尔茨海默相关痴呆 以及社会经济地位等。这项研究还将深入探讨非正式的差异 照顾患有认知障碍和痴呆症的墨西哥裔美国人和非西班牙裔白人。看护者 将检查护理人员的负担以及身心健康，以制定干预措施 增强护理人员的适应力。这项基于人群的研究的一项新颖功能是检查社区 患者和护理人员的资源，以及这些规定如何因种族而异。采用严格的混合 方法方法我们将确定可用资源与认知能力障碍者的需求之间的差距 损伤和痴呆。通过这种方式，我们将能够很好地提出针对特定种族的可测试方案 促进认知障碍和痴呆症患者身心健康的干预措施，例如 以及那些提供照顾的家庭成员。因此，这项研究将导致改善 认知障碍和痴呆症患者及其照顾者的存在、自主权和结果。 调查小组成员在该社区进行了20年的研究，是以下领域的专家： 墨西哥裔美国人文化与健康、认知障碍和痴呆、流行病学方法、社区 需求评估和健康行为研究。随着墨西哥裔美国人人口继续增长 巨大的增长和老龄化，更好地了解其患病率和结果至关重要 该人群的认知障碍和痴呆症，并迅速制定解决这些问题的干预措施 这些常见状况给墨西哥裔美国成年人、家庭和社区带来了负担。

项目成果

A community-based study of reporting demographic and clinical information concordance between informants and cognitively impaired participants.

一项基于社区的研究，报告知情者和认知障碍参与者之间的人口统计和临床信息一致性。

• DOI: 10.1007/s40520-023-02435-6
• 发表时间: 2023
• 期刊: Aging clinical and experimental research
• 影响因子: 4
• 作者: Khan,Noreen;Briceño,EmilyM;Mehdipanah,Roshanak;Lewandowski-Romps,Lisa;Heeringa,StevenG;Garcia,Nelda;Levine,DeborahA;Langa,KennethM;Morgenstern,LewisB
• 通讯作者: Morgenstern,LewisB

A Community-Based Study of Dementia in Mexican American and Non-Hispanic White Individuals.

墨西哥裔美国人和非西班牙裔白人痴呆症的社区研究。

• DOI: 10.3233/jad-230729
• 发表时间: 2024
• 期刊: Journal of Alzheimer's disease : JAD
• 作者: Morgenstern,LewisB;Briceño,EmilyM;Mehdipanah,Roshanak;Chang,Wen;Lewandowski-Romps,Lisa;Gonzales,XavierF;Levine,DeborahA;Langa,KennethM;Garcia,Nelda;Khan,Noreen;Zahuranec,DarinB;Heeringa,StevenG
• 通讯作者: Heeringa,StevenG