The 2003 Gordon Conference on Elastin and Elastic Tissue

2003 年戈登弹性蛋白和弹性组织会议

• 批准号: 6680447
• 负责人: STEVEN D SHAPIRO
• 金额: $ 1.5万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-19 至 2004-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6680447
• 关键词: elastic tissue; elastin; meeting /conference /symposium; travel

DESCRIPTION (provided by applicant): This application requests funds to provide support for the twelfth bi-annual Gordon Research Conference on Elastin and Elastic Fibers to be held from August 3-8, 2003. The objective of this meeting is to provide a format for the exchange and integration of new information on the molecular and cell biology, biochemistry, biosynthesis, assembly, and pathobiology of elastin and micro fibrils. The proposed meeting will bring together basic scientists from a variety of disciplines to present and discuss the most recent information on elastin and microfibrillar proteins. This Conference will act as a major stimulus for international research into the nature and function of these unusual and important connective tissue proteins. Many novel findings related to elastic and microfibrillar proteins have been made since the 2001 Elastin and Elastic Fiber Gordon Conference. Among these include the role of elastic fibers in development and other biological processes, their utility in biomaterials and tissue engineering, and insights into their function and role in diseases such as COPD from functional genomics. In addition, much new biological functions of elastases have also been achieved largely through gene targeting. These functions include inflammatory functions as well as host defense against tumor progression and microbes. Thus, the 2003 Elastin and Elastic Fiber Gordon Conference will occur at an exciting time in connective tissue biology and will provide a mechanism to discuss these new findings. As in past years, these personal interactions will result in new collaborative studies and stimulate novel avenues of investigation of these important matrix proteins.

描述（由申请人提供）：本申请要求资金为将于2003年8月3日至8日举行的第十二届弹性蛋白和弹性纤维两年一度的戈登研究会议提供支持。本次会议的目的是提供一个格式的分子和细胞生物学，生物化学，生物合成，组装和病理生物学的弹性蛋白和微纤维的新信息的交流和整合。拟议的会议将汇集来自不同学科的基础科学家，介绍和讨论弹性蛋白和微纤维蛋白的最新信息。这次会议将作为一个重大的刺激国际研究的性质和功能，这些不寻常的和重要的结缔组织蛋白质。自2001年弹性蛋白和弹性纤维戈登会议以来，已经取得了许多与弹性和微纤维蛋白相关的新发现。其中包括弹性纤维在发育和其他生物过程中的作用，它们在生物材料和组织工程中的用途，以及从功能基因组学中了解它们在COPD等疾病中的功能和作用。此外，弹性蛋白酶的许多新的生物学功能也在很大程度上通过基因打靶实现。这些功能包括炎症功能以及针对肿瘤进展和微生物的宿主防御。因此，2003年弹性蛋白和弹性纤维戈登会议将发生在一个令人兴奋的时刻，在结缔组织生物学，并将提供一个机制，讨论这些新的发现。与过去几年一样，这些个人互动将导致新的合作研究，并刺激研究这些重要基质蛋白的新途径。