FASEB Summer Research Conf.- Chromatin and Transcription

描述（由申请人提供）：对抗疾病的能力在很大程度上取决于对基因表达如何驱动发育和维持生命的坚实理解。 为此，建议的会议引人注目的主要目标是澄清染色质控制基因表达的方式，无论是在单基因水平还是在整个基因组水平。 该会议将构成两年一度的FASEB染色质和转录夏季研究会议的第7次会议，该系列会议从一开始就被国际公认为该领域最重要的两次会议之一，另一次是隔年举行的姐妹戈登会议。 到目前为止，27名受访者中100%同意参加，每个人都是其领域无可争议的领导者。 因此，毫无疑问，这次会议，像它的前任，将举办基因调控的重要进展。 为了最大限度地提高会议的成功，共同组织者致力于1）引入来自染色质，转录和基因组组织不同领域的专家，以便通过通常不会见面的研究人员之间的协同作用加强会议，2）引入新问题并提出新问题，3）通过促进年轻研究人员的职业生涯来确保该领域的未来。 目前，该计划将包括九个平台和两个海报会议，预计总出席人数将达到200人，其中包括60名发言人。 虽然该方案预计将不断发展，但目前的会议标题是： I.组蛋白修饰 二.核小体结构和重塑 三.复制、组装、修理、维护和隔离 四.高阶结构和调节 诉非编码RNA与调控 六.染色质结构的发育作用 七.高阶效应与发展 八.转录I 九.转录II

DESCRIPTION (provided by applicant): The ability to combat disease depends to a great extent on a solid understanding of how gene expression drives development and maintains life. To this end, the compelling primary goal of the proposed conference is to clarify the manner in which chromatin controls gene expression, both at the level of the single gene and at the level of the whole genome. The conference will constitute the 7th meeting of the biennial FASEB Summer Research Conference on Chromatin and Transcription, a series that, from its inception, has been internationally recognized as one of the two most important meetings in the field, the other being its sister Gordon Conference held in alternate years. Thus far, 100% of 27 respondents have agreed to attend, each one an undisputed leader in his or her field. As such, there is no doubt that this conference, like its predecessors, will host important advances in gene regulation. In order to maximize the success of the conference, the co-organizers are committed to 1) bringing in experts from diverse fields of chromatin, transcription, and genome organization, so that the conference can be strengthened by synergy between researchers who would not normally meet, 2) introducing new issues and raising new questions, and 3) assuring the future of the field by promoting the careers of young investigators. At present the program will consist of nine platform and two poster sessions, and total attendance is expected to be ~200, including ~60 speakers. While the program is expected to evolve, the session titles are, at present: I. Histone Modification II. Nucleosomal structure and remodeling III. Replication, assembly, repair, maintenance, and segregation IV. Higher order structure and regulation V. Non-coding RNAs and regulation VI. Developmental roles of chromatin structure VII. Higher order effects and development VIII. Transcription I IX. Transcription II