FASEB Summer Research Conf.- Chromatin and Transcription

描述（由申请人提供）：对抗疾病的能力在很大程度上取决于对基因表达如何驱动发育和维持生命的深刻理解。为此，本次会议的主要目标是阐明染色质在单基因水平和全基因组水平上控制基因表达的方式。该会议将构成两年一次的FASEB夏季染色质和转录研究会议的第七次会议，该系列会议从一开始就被国际公认为该领域最重要的两个会议之一，另一个是其姊妹会议戈登会议，每隔一年举行一次。到目前为止，27名受访者中100%同意参加，每个人都是他或她所在领域无可争议的领导者。因此，毫无疑问，这次会议将像其前任一样，在基因调控方面取得重要进展。

DESCRIPTION (provided by applicant): The ability to combat disease depends to a great extent on a solid understanding of how gene expression drives development and maintains life. To this end, the compelling primary goal of the proposed conference is to clarify the manner in which chromatin controls gene expression, both at the level of the single gene and at the level of the whole genome. The conference will constitute the 7th meeting of the biennial FASEB Summer Research Conference on Chromatin and Transcription, a series that, from its inception, has been internationally recognized as one of the two most important meetings in the field, the other being its sister Gordon Conference held in alternate years. Thus far, 100% of 27 respondents have agreed to attend, each one an undisputed leader in his or her field. As such, there is no doubt that this conference, like its predecessors, will host important advances in gene regulation. In order to maximize the success of the conference, the co-organizers are committed to 1) bringing in experts from diverse fields of chromatin, transcription, and genome organization, so that the conference can be strengthened by synergy between researchers who would not normally meet, 2) introducing new issues and raising new questions, and 3) assuring the future of the field by promoting the careers of young investigators. At present the program will consist of nine platform and two poster sessions, and total attendance is expected to be ~200, including ~60 speakers. While the program is expected to evolve, the session titles are, at present: I. Histone Modification II. Nucleosomal structure and remodeling III. Replication, assembly, repair, maintenance, and segregation IV. Higher order structure and regulation V. Non-coding RNAs and regulation VI. Developmental roles of chromatin structure VII. Higher order effects and development VIII. Transcription I IX. Transcription II