Microfluidic approach toward continuous synthesis of metal organic framework (MOF) crystals

连续合成金属有机骨架（MOF）晶体的微流控方法

• 批准号: 2282152
• 金额: --
• 依托单位: University of Leeds
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2282152
• 关键词: Microfluidic; approach; toward; continuous; synthesis

Aims and objectives: To research and develop synthesis techniques for the microfluidic synthesis of MOF structures, with the MOF structures produced having known applications in a variety of areas. To test the properties and performance of MOFs produced against those formed through batch processes. To scale up the production to Kg/day scaleApplications and benefits:Metal Organic Frameworks (MOFs) are porous crystalline materials, constructed by metal ions and organic polyfunctional ligands. They have shown promise in a wide range of applications such as gas storage, chemical separations, catalysis, drug delivery, etc. To meet their large-scale applications requirements, the development of facile and effective synthetic methods of MOFs is highly desirable. Microfluidics technology offered a qualitatively superior alternative to conventional batch process for MOFs synthesis. By using microfluidic devices, 1) a number of MOFs can be manufactured without the need of bespoke equipment for each synthesis; 2) a fast synthesis of MOFs can be achieved without a loss in product quality and moreover with a precise control over their size and shape; and 3) a simple 'number-up' strategy can be applied to produce MOFs with quantities approaching those required for widespread application. The initial plan for this project is to develop a droplet-based microfluidic synthesis route for UiO-67, which has not been previously investigated. This MOF has shown potential for applications in H2 capture and storage, CO2 capture and storage, and a range of catalytic processes. Once the non-modified form of UiO-67 has been made through this process, then the focus will shift to forming a functionalised form of UiO-67 for a specific application.The proposed research fits well into several research areas within the EPSRC engineering portfolio, e.g. Microsystems and Manufacturing Technologies

目的和目标：研究和开发用于MOF结构的微流体合成的合成技术，所产生的MOF结构在各种领域中具有已知的应用。 测试生产的MOFs与通过批处理形成的MOFs的性质和性能。将生产规模扩大到Kg/天应用和优势：金属有机框架（MOFs）是由金属离子和有机多官能配体构成的多孔晶体材料。它们在气体储存、化学分离、催化、药物递送等广泛的应用中显示出了希望。为了满足其大规模应用的要求，开发简便有效的MOFs合成方法是非常可取的。微流控技术为MOFs的合成提供了一种质量上优于传统间歇工艺的上级方法。通过使用微流体装置，1）可以制造许多M0 F，而不需要用于每次合成的定制设备; 2）可以实现M0 F的快速合成，而不会损失产品质量，并且还可以精确控制它们的尺寸和形状;以及3）可以应用简单的“编号”策略来生产具有接近广泛应用所需的量的M0 F。该项目的初步计划是为UiO-67开发一种基于液滴的微流控合成路线，这是以前没有研究过的。这种MOF在H2捕获和储存、CO2捕获和储存以及一系列催化过程中显示出应用潜力。一旦UiO-67的未修饰形式通过该过程制成，那么重点将转移到形成用于特定应用的UiO-67的功能化形式。拟议的研究非常适合EPSRC工程组合中的几个研究领域，例如微系统和制造技术