FACILITIES CONSTRUCTION BIOCHEMISTRY RENEWAL PROJECT

描述（由申请人提供）： 我们建议在健康科学综合大楼的J翼的第3，4和5层翻新30，706 NSF的研究空间。 自1965年J翼建成以来，这个空间一直没有翻新，占生物化学系实验室和支持空间的约60%。 拟议的翻新将通过彻底的重新设计促进NIH资助的部门研究，允许每个实验室有更多的工作人员，实验室内部和实验室之间有更多的互动，共享使用位于公共支持室的昂贵的主要设备，以及随着研究小组的增长和缩小而灵活分配空间。 虽然位于医学院，生物化学系作为医学和基础科学之间的桥梁，并保持一个大的本科专业，以及教学医学生和研究生。 该部门的研究使命是了解大分子如何进行和调节生物过程。 兴趣涵盖从分子生物物理学到发育生物学的全方位。 翻新后的空间将由四名新的助理教授和十三名现任教师占用，他们都得到了NIH的支持。 虽然，许多教师即将退休，该部门已经开始纠正目前的年龄不平衡，招聘新的初级教师，预计未来的退休。 因此，拟议中的翻新将加强正在进行的NIH资助的研究项目，并使一个具有杰出历史的部门能够吸引新的NIH资助的教师到一个更老的，但基本上是健全的，建设。

DESCRIPTION (provided by applicant): We propose renovation of 30,706 NSF of research space on the 3rd, 4th, and 5th floors of the J-wing in the Health Sciences Complex. This space has not been renovated since J-wing was completed in 1965, and represents approximately 60% of the laboratory and support space occupied by the Department of Biochemistry. The proposed renovation will facilitate NIH-funded research in the department by a thorough redesign that allows more bench workers per laboratory, greater interactions within and between laboratories, shared use of costly major equipment located in common support rooms, and flexible allocation of space as research groups grow and shrink. Although located in the School of Medicine, the Department of Biochemistry serves as a bridge between the medical and the basic sciences, and maintains a large undergraduate major as well as teaching medical students and graduate students. The research mission of the department is to understand how macromolecules carry out and regulate biological processes. Interests span the full-range from molecular biophysics to developmental biology. The renovated space would be occupied by four new assistant professors and thirteen current faculty, all of whom have NIH support. Although, many faculty are approaching retirement, the department has already begun to redress the current age imbalance by recruiting new junior faculty in anticipation of future retirements. Thus, the proposed renovation will strengthen ongoing NIH funded research programs, and enable a department with a distinguished history to attract new NIH funded faculty to an older, but essentially sound, building.