FACILITIES CONSTRUCTION BIOCHEMISTRY RENEWAL PROJECT

描述(由申请人提供)： 我们建议在健康科学综合体J翼的3、4和5层翻新30,706个NSF的研究空间。自1965年J翼建成以来，这个空间一直没有翻修过，大约占生化系实验室和支持空间的60%。拟议的翻修将通过彻底的重新设计来促进NIH资助的部门内的研究，允许每个实验室有更多的长凳工人，实验室内部和实验室之间有更多的互动，共享位于公共支持室的昂贵的主要设备，以及随着研究小组的增长和缩减灵活分配空间。虽然生物化学系位于医学院，但它是连接医学和基础科学的桥梁，并保持着庞大的本科专业以及医学生和研究生的教学。该部门的研究任务是了解大分子如何进行和调节生物过程。兴趣横跨从分子生物物理学到发育生物学的各个领域。翻新后的空间将由4名新的助理教授和13名现任教职员工占用，他们都得到了NIH的支持。尽管许多教员即将退休，但该系已经开始通过招聘新的初级教员来纠正目前的年龄失衡，预计未来将会退休。因此，拟议的翻修将加强正在进行的NIH资助的研究项目，并使一个拥有杰出历史的系能够吸引新的NIH资助的教师来到一座更老但基本上健全的建筑。

DESCRIPTION (provided by applicant): We propose renovation of 30,706 NSF of research space on the 3rd, 4th, and 5th floors of the J-wing in the Health Sciences Complex. This space has not been renovated since J-wing was completed in 1965, and represents approximately 60% of the laboratory and support space occupied by the Department of Biochemistry. The proposed renovation will facilitate NIH-funded research in the department by a thorough redesign that allows more bench workers per laboratory, greater interactions within and between laboratories, shared use of costly major equipment located in common support rooms, and flexible allocation of space as research groups grow and shrink. Although located in the School of Medicine, the Department of Biochemistry serves as a bridge between the medical and the basic sciences, and maintains a large undergraduate major as well as teaching medical students and graduate students. The research mission of the department is to understand how macromolecules carry out and regulate biological processes. Interests span the full-range from molecular biophysics to developmental biology. The renovated space would be occupied by four new assistant professors and thirteen current faculty, all of whom have NIH support. Although, many faculty are approaching retirement, the department has already begun to redress the current age imbalance by recruiting new junior faculty in anticipation of future retirements. Thus, the proposed renovation will strengthen ongoing NIH funded research programs, and enable a department with a distinguished history to attract new NIH funded faculty to an older, but essentially sound, building.