Novel peptide-based modulators to enhance immunotherapy in cancer

新型肽调节剂可增强癌症免疫治疗

• 批准号: 2284229
• 金额: --
• 依托单位: Imperial College London
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2284229
• 关键词: Novel; peptide; based; modulators; enhance

Therapeutic antibodies and cell therapies have rapidly become the fastest growing class of new immunotherapy treatments for a range of diseases, particularly caner. However, in many cases patients fail to respond or develop resistance. Here we will design, chemically synthesise and test new peptide-based compounds which can modulate the response to immunotherapy, potentially restoring response to treatment.

治疗性抗体和细胞疗法已迅速成为增长最快的一类新的免疫疗法治疗一系列疾病，特别是癌症。然而，在许多情况下，患者没有反应或产生耐药性。在这里，我们将设计，化学合成和测试新的基于肽的化合物，可以调节免疫治疗的反应，可能恢复对治疗的反应。