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Low-Cost Collimators for Nuclear Medicine Imaging

用于核医学成像的低成本准直器

基本信息

批准号：
6725620
负责人：
MICHAEL P APPLEBY
金额：
$ 14万
依托单位：
MIKRO SYSTEMS, INC.
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-09-08 至 2004-08-31
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): The long-term objective of the proposed R21 effort is to reduce the cost and improve the quality of medical imaging, thereby improving detection, diagnosis, and therapy for a number of human health diseases. The specific aim of this research is to fabricate advanced high-resolution collimators for nuclear medicine imaging at a significantly lower cost than currently is possible. An innovative fabrication technology will be used to produce advanced high-resolution collimators made from an improved material (tungsten powder composite). The combination of a new fabrication method and new collimator materials offer important advantages in terms of design flexibility and performance over current collimator fabrication techniques. This is an enabling technology. Most importantly, it has the potential to allow very high-performance collimators to be produced at a relatively low cost. The proposed exploratory effort will demonstrate technical feasibility by fabricating prototype low energy high-resolution (LEHR) collimators employing a dense (approximately 11 g/cc) composite material, and comparing their dimensional accuracy and imaging performance against state-of-the-art LEHR collimators commercially available. Potential commercial applications include nuclear medicine (small and large format cameras), computed tomography, mammography, as well as non-medical applications such as astrophysics, non-destructive testing, and security scanners.

描述（由申请人提供）： R21计划的长期目标是降低医疗成像的成本并提高其质量，从而改善对许多人类健康疾病的检测、诊断和治疗。这项研究的具体目标是以比目前更低的成本制造用于核医学成像的先进高分辨率准直器。一种创新的制造技术将用于生产先进的高分辨率准直器，该准直器由改进的材料（钨粉复合材料）制成。新的制造方法和新的准直器材料的组合在设计灵活性和性能方面提供了优于当前准直器制造技术的重要优势。这是一项使能技术。最重要的是，它有可能以相对较低的成本生产非常高性能的准直器。拟议的探索性工作将证明技术可行性，制造原型低能量高分辨率（LEHR）准直器采用致密（约11克/立方厘米）的复合材料，并比较其尺寸精度和成像性能对国家的最先进的LEHR准直器市售。潜在的商业应用包括核医学（小型和大型相机），计算机断层扫描，乳房X射线摄影，以及非医疗应用，如天体物理学，无损检测和安全扫描仪。