Biology of Infectious Diseases & Inflammation

描述（由申请人提供）：本提案是一项竞争性更新培训补助金的请求，以资助我们的传染病和炎症计划（IDIP）的四名博士前和两名博士后学员。IDIP由19名受资助的研究人员组成，他们都被列为该补助金的学员，我们的学员，初级教师（未列出培训师）以及支持传染病和炎症研究的行政和技术人员。教师的专业领域可以大致分为四个感兴趣的领域：重新出现的细菌感染的发病机制（3），生物防御和新兴病毒感染（5），癌症作为一种传染性病毒疾病（3）和基本炎症和免疫机制（8）。培训教师包括17名在新墨西哥州（UNM）医学院（SOM）四个部门任职的人，包括内科（4），分子遗传学和微生物学（6），病理学（6）和细胞生物学和生理学（1）]或Lovelace呼吸研究所（2）。培训计划的目标是：1）通过提供研究报告、期刊俱乐部、研讨会和课程开发的场所，丰富传染病和炎症的跨学科研究; 2）为博士前和博士后学员提供丰富的合作教育研究环境，让他们有机会向各种科学家、技术人员和其他学员学习; 3）提供专业指导，包括科学道德、教学和各种科学职业机会方面的指导和经验培训。该计划是从那些已经在UNM SOM的跨学科生物医学科学研究生课程（BSGP）中录取的博士前学生中招募奖学金学员，他们选择在IDIP教师的实验室工作。博士后候选人将从DIP教师实验室招募的合格博士后培训生中选出。选定的受训人员将由其具体的IDIP培训员进行指导（博士前学生获得两到三年的培训补助金支持，博士后受训人员获得两年的培训补助金支持），IDIP指导委员会将定期审查他们的进展情况。所有人都将参加IDIP特定的课程，除了那些课程，博士前学员必须采取由BSGP指定。该计划得到了UNM SOM和LRRI的大力支持，SOM或LRRI联合资助所有一年级学生，并联合BSGP和部门支持该计划的管理，包括所有招聘费用。我们的计划包括具体和不寻常的优势，因为受训者接触到教学培训和实验室经验，这些经验非常广泛，使他们接触到优秀的跨学科核心设施，强大的生物技术，（企业）合作、国际项目（如ICIDR/Fogarty计划），与高致病性潜在生物武器，高超的结构生物学和成像能力，和发达的生物工程研究伙伴关系。

DESCRIPTION (provided by applicant): This proposal is a request for competitive renewal of a training grant to fund four predoctoral and two postdoctoral trainees in our Infectious Disease and Inflammation Program (IDIP). IDIP is comprised of a group of 19 funded investigators, all listed as trainees on this grant, our trainees, junior faculty (not listed a trainers) and administrative and technical staff who support research in infectious disease and inflammation. The areas of expertise of the faculty can be broadly grouped into four areas of interest: Pathogenesis of Reemerging Bacterial Infections (3), Biodefense and Emerging Viral Infections (5), Cancer as a Communicable Viral Disease (3) and Basic Inflammatory and Immunologic Mechanisms (8). The training faculty include 17 who have appointments in four University of New Mexico (UNM) School of Medicine (SOM) departments that include Internal Medicine (4), Molecular Genetics and Microbiology (6), Pathology (6), and Cell biology and Physiology (1)] or at Lovelace Respiratory Research Institute (2). The goals of the training program are to: 1) enrich interdisciplinary research in infectious diseases and inflammation by providing venues for research presentations, journal clubs, seminars and course development; 2) provide a rich, cooperative educational research environment with opportunities for both pre- and postdoctoral trainees to learn from a wide variety of scientists, their technicians and other trainees; and 3) to provide professional guidance, including instruction and experiential training in scientific ethics, teaching, and opportunities in diverse scientific careers. The plan is to recruit fellowship trainees from among those predoctoral students who have already matriculated in UNM SOM's interdisciplinary Biomedical Sciences Graduate Program (BSGP) who choose to work in the laboratories of IDIP faculty member. The postdoctoral candidates will be selected from qualified postdoctoral trainees recruited to DIP faculty laboratories. The selected trainees would be mentored (with two to three years of training grant support for predoctoral students and two years for postdoctoral trainees) by their specific IDIP trainer, and their progress will be regularly reviewed by the IDIP steering committee. All would be expected to take IDIP-specific courses, in addition to those courses that the predoctoraI trainees are required to take as specified by the BSGP. The program is strongly supported by both UNM SOM and the LRRI as evidenced by the SOM or LRRI jointly funding fully all first year students and by joint BSGP and departmental support for administration of the program, including all recruiting costs. Our program includes specific and unusual strengths in that trainees are exposed to didactic training and laboratory experiences that are very broad and that expose them to excellent interdisciplinary core facilities, strong biotechnotogy (corporate) collaborations, international programs (such as an ICIDR/Fogarty program), work with highly pathogenic potential bioweapons, superb structural biology and imaging capabilities, and well-developed bioengineering research partnerships.