Biology of Infectious Diseases & Inflammation

描述(由申请人提供)：本提案是一项竞争性更新培训补助金的申请，用于资助我们传染病和炎症项目(IDIP)的四名博士后和两名博士后学员。IDIP由19名受资助的研究人员组成，所有人都被列为这笔赠款的实习生，我们的实习生、初级教员(没有被列为培训者)以及支持传染病和炎症研究的行政和技术人员。该学院的专业领域大致可分为四个感兴趣的领域：新出现的细菌感染的发病机制(3)、生物防御和新出现的病毒感染(5)、作为一种传染性病毒疾病的癌症(3)以及基本的炎症和免疫机制(8)。培训人员包括17人，他们在新墨西哥大学医学院(SOM)的四个系(包括内科(4个)、分子遗传学和微生物学(6个)、病理学(6个)和细胞生物学和生理学(1个))或洛夫莱斯呼吸研究所(2个)任职。培训计划的目标是：1)通过提供研究报告、期刊俱乐部、研讨会和课程开发的场所，丰富传染病和炎症的跨学科研究；2)提供丰富的、合作的教育研究环境，为博士后和博士后学员提供向各种科学家、他们的技术人员和其他学员学习的机会；以及3)提供专业指导，包括关于科学道德、教学和不同科学职业机会的指导和经验培训。该计划将从那些已经在新墨西哥州州立大学高级管理学院的跨学科生物医学研究生计划(BSGP)录取的博士前学员中招募选择在IDIP教员的实验室工作的研究员。博士后候选人将从招聘到DIP教师实验室的合格博士后实习生中挑选出来。被选中的学员将由其特定的IDIP培训师指导(为博士前学生提供两至三年的培训补助金支持，为博士后学员提供两年的培训补助金支持)，IDIP指导委员会将定期审查他们的进展情况。除了BSGP规定的博士前培训学员必须参加的课程外，所有人都将参加IDIP特定的课程。该计划得到了UNM SOM和LRRI的大力支持，这一点体现在SOM或LRRI共同为所有一年级学生提供全额资金，以及BSGP和部门对该计划管理的联合支持，包括所有招生成本。我们的计划包括独特和不同寻常的优势，因为学员可以接触到非常广泛的教学培训和实验室经验，使他们能够接触到优秀的跨学科核心设施、强大的生物技术(企业)合作、国际计划(如ICIDR/Fogarty计划)、与高致病性潜在生物武器的合作、高超的结构生物学和成像能力，以及发展良好的生物工程研究伙伴关系。

DESCRIPTION (provided by applicant): This proposal is a request for competitive renewal of a training grant to fund four predoctoral and two postdoctoral trainees in our Infectious Disease and Inflammation Program (IDIP). IDIP is comprised of a group of 19 funded investigators, all listed as trainees on this grant, our trainees, junior faculty (not listed a trainers) and administrative and technical staff who support research in infectious disease and inflammation. The areas of expertise of the faculty can be broadly grouped into four areas of interest: Pathogenesis of Reemerging Bacterial Infections (3), Biodefense and Emerging Viral Infections (5), Cancer as a Communicable Viral Disease (3) and Basic Inflammatory and Immunologic Mechanisms (8). The training faculty include 17 who have appointments in four University of New Mexico (UNM) School of Medicine (SOM) departments that include Internal Medicine (4), Molecular Genetics and Microbiology (6), Pathology (6), and Cell biology and Physiology (1)] or at Lovelace Respiratory Research Institute (2). The goals of the training program are to: 1) enrich interdisciplinary research in infectious diseases and inflammation by providing venues for research presentations, journal clubs, seminars and course development; 2) provide a rich, cooperative educational research environment with opportunities for both pre- and postdoctoral trainees to learn from a wide variety of scientists, their technicians and other trainees; and 3) to provide professional guidance, including instruction and experiential training in scientific ethics, teaching, and opportunities in diverse scientific careers. The plan is to recruit fellowship trainees from among those predoctoral students who have already matriculated in UNM SOM's interdisciplinary Biomedical Sciences Graduate Program (BSGP) who choose to work in the laboratories of IDIP faculty member. The postdoctoral candidates will be selected from qualified postdoctoral trainees recruited to DIP faculty laboratories. The selected trainees would be mentored (with two to three years of training grant support for predoctoral students and two years for postdoctoral trainees) by their specific IDIP trainer, and their progress will be regularly reviewed by the IDIP steering committee. All would be expected to take IDIP-specific courses, in addition to those courses that the predoctoraI trainees are required to take as specified by the BSGP. The program is strongly supported by both UNM SOM and the LRRI as evidenced by the SOM or LRRI jointly funding fully all first year students and by joint BSGP and departmental support for administration of the program, including all recruiting costs. Our program includes specific and unusual strengths in that trainees are exposed to didactic training and laboratory experiences that are very broad and that expose them to excellent interdisciplinary core facilities, strong biotechnotogy (corporate) collaborations, international programs (such as an ICIDR/Fogarty program), work with highly pathogenic potential bioweapons, superb structural biology and imaging capabilities, and well-developed bioengineering research partnerships.