Core--Statistical Facility

核心——统计设施

• 批准号: 6866210
• 负责人: SONDRA PERDUE
• 金额: $ 22.99万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6866210
• 关键词: biomedical facility; computer center; cooperative study; data collection; human data; sexually transmitted diseases; statistical service /center

The Statistical/Computing Core is an indispensable component of the San Antonio STI TM CRC proposal, providing the data collection and organizational backbone for all physical examinations, clinical questionnaires, behavioral questionnaires, and laboratory assays, as well as all study clinic activities, including subject/dyad tracking and required reporting to health departments. Members of the Statistics/Computing Core will ensure the continued integrity of the Research Projects by overseeing data collection and ensuring the proper linkage of the various components of the STI TM CRC. These tasks will be accomplished through the use of a customized multi-functional database developed and maintained by Core personnel. In addition, the Statistical/Computing Core will provide expertise in computer hardware and software, including maintaining and upgrading all computer systems encompassed within the STI TM CRC. Finally, after data have been collected, members of the Statistical/Computing Core, with expertise in epidemiologic study design, statistical analysis techniques, and computer programming, will provide a central support system for all data analysis and interpretation activities undertaken by the Research Projects comprising the STI TM CRC, and will implement appropriate analytic methods for collaboratively addressing all Project Aims that involve statistical data analysis. Members of the Statistical/Computing Core will be closely integrated with each Project, providing specimen tracking and identification, as well as linkage of specimens across time within patients and dyads. Data collected at each visit for the Behavioral Project will be linked to results obtained from the Microbiology Research Projects and the Clinical Project in order to correlate laboratory findings with concurrent clinical, behavioral, situational, and other characteristics of the subjects. For the Behavioral Project in particular, Statistical/Computing Core personnel will be integrally involved at every step of the data analysis, including the assessment of intervention impact, the development of complex variable constructs, and the examination of numerous research questions relating to the understanding and prevention of STI transmission.

统计/计算核心是圣安东尼奥STI TM CRC提案不可或缺的组成部分，为所有体检、临床问卷、行为问卷和实验室分析以及所有研究诊所活动提供数据收集和组织支柱，包括受试者/对偶追踪和要求向卫生部门报告。统计/计算核心的成员将通过监督数据收集和确保STI TM CRC各组成部分之间的适当联系，确保研究项目的持续完整性。这些任务将通过使用由核心人员开发和维护的定制多功能数据库来完成。此外，统计/计算核心将提供计算机硬件和软件方面的专门知识，包括维护和升级STI TM CRC所包含的所有计算机系统。最后，在收集数据后，具有流行病学研究设计、统计分析技术和计算机编程专长的统计/计算核心成员将为组成STI TM CRC的研究项目进行的所有数据分析和解释活动提供中央支助系统，并将实施适当的分析 协作解决涉及统计数据分析的所有项目目标的方法。统计/计算核心的成员将与每个项目密切结合，提供样本跟踪和鉴定，以及在患者和双生子内的不同时间将样本联系起来。行为项目每次访问时收集的数据将与微生物学研究项目和临床项目获得的结果相关联，以便将实验室结果与受试者的临床、行为、情景和其他特征相关联。特别是对于行为项目，统计/计算核心人员将全面参与数据分析的每一个步骤，包括评估干预影响、制定复杂的变量结构以及审查与了解和预防性传播感染有关的许多研究问题。