Development of Simulations to Detect Impaired Drivers

描述：美国数百万人受到痴呆症的影响 紊乱在保险箱中检测这些人的驾驶障碍， 可靠和具有成本效益的方式仍然是一项艰巨的挑战。的 第二阶段的总体目标是完成新的、低成本的 基于PC的计算机驾驶模拟，适用于评估 不同患者组在多项评估中的驾驶能力。通过 完成最后的发展，技术先进，心理测量 声音驾驶模拟，我们希望进一步的科学研究“真实的 生活”的结果，并使这些新的工具提供给研究和 临床社区该项目的具体目标是：（1）加强 软件的技术能力，（2）提高灵敏度， 第一阶段开发的测试场景的可靠性，（3）建立 模拟器的有效性，使用道路上的评价，在不同的患者 神经认知概况，以及（4）建立模拟的有效性 对于纵向评估，通过检查可能随时间变化的患者 6个月随访。由于驾驶技术可能会受到痴呆症的影响， 以及药物，预计这项技术将有 良好的商业可行性和广泛的适用性， 研究、治疗试验和临床评估。 拟定商业应用： 开发一种高保真、低成本的驾驶模拟器，该模拟器在多个患者群体中纵向地得到很好的验证，这将为评估与驾驶相关的“真实的生活”功能提供重要的工具。潜在的市场包括受损驾驶员的评估，药物副作用的监测，驾驶员培训和康复（酒精，药物，头部受伤，残疾，中风等），司机教育。

DESCRIPTION: Millions of individuals in the U.S. are affected by dementing disorders. Detecting driving impairments in these individuals in a safe, reliable and cost-efficient manner remains a formidable challenge. The overarching goal of Phase II is to complete development of novel, low-cost PC-based computer driving simulations that are valid for the assessment of driving abilities in varied patient groups over multiple assessments. By completing final development of technologically advanced, psychometrically sound driving simulations we hope to further the scientific study of "real life" outcomes, and make these novel tools available to the research and clinical community. The specific aims of this project are (1) to enhance the technological capabilities of software, (2) to improve the sensitivity and reliability of the test scenarios developed in Phase I, (3) to establish simulator validity using on-road evaluations in patients with varied neurocognitive profiles, and (4) to establish the validity of the simulations for longitudinal assessments by examining patients who are likely change over a 6 month follow-up. Since driving skills may be affected by dementing disorders, as well as medications, it is anticipated that this technology will have excellent commercial viability and broad applicability for neurobehavioral research, treatment trials, and clinical assessments. PROPOSED COMMERCIAL APPLICATION: Development of a high fidelity, low cost driving simulator that is well-validated across multiple patient groups longitudinally will provide a significant tool for the assessment of "real life" functioning as it relates to driving. Potential markets include assessment of impaired drivers, monitoring of medication side effects, driver training and rehabilitation (alcohol, drugs, head injuries, disabilities, strokes, etc.), and driver education.