Development of Simulations to Detect Impaired Drivers

描述：美国数以百万计的人患有痴呆症 精神错乱。在保险箱中检测这些人的驾驶障碍， 可靠和具有成本效益的方式仍然是一项艰巨的挑战。这个 第二阶段的总体目标是完成新的、低成本的开发 基于PC的计算机驾驶模拟，可用于评估 不同患者群体在多项评估中的驾驶能力。通过 完成先进技术的最终开发，心理测量学 我们希望通过声音驾驶模拟来进一步科学研究“真实” 结果，并使这些新工具可用于研究和 临床社区。这项计划的具体目标是：(1)加强 软件的技术能力，(2)提高灵敏度和 在阶段I中开发的测试场景的可靠性，(3)建立 模拟器在不同疾病患者道路评估中的有效性 神经认知特征，以及(4)建立模拟的有效性 通过检查可能在一年内发生变化的患者进行纵向评估 6个月随访。由于驾驶技能可能会受到痴呆症的影响， 除了药物，预计这项技术将有 卓越的商业可行性和广泛的神经行为应用 研究、治疗试验和临床评估。 建议的商业应用： 开发一种高保真、低成本的驾驶模拟器，纵向上在多个患者群体中得到很好的验证，将为评估与驾驶有关的“现实生活”功能提供一个重要工具。潜在市场包括对受损司机的评估、药物副作用的监测、司机培训和康复(酒精、药物、头部受伤、残疾、中风等)，以及司机教育。

DESCRIPTION: Millions of individuals in the U.S. are affected by dementing disorders. Detecting driving impairments in these individuals in a safe, reliable and cost-efficient manner remains a formidable challenge. The overarching goal of Phase II is to complete development of novel, low-cost PC-based computer driving simulations that are valid for the assessment of driving abilities in varied patient groups over multiple assessments. By completing final development of technologically advanced, psychometrically sound driving simulations we hope to further the scientific study of "real life" outcomes, and make these novel tools available to the research and clinical community. The specific aims of this project are (1) to enhance the technological capabilities of software, (2) to improve the sensitivity and reliability of the test scenarios developed in Phase I, (3) to establish simulator validity using on-road evaluations in patients with varied neurocognitive profiles, and (4) to establish the validity of the simulations for longitudinal assessments by examining patients who are likely change over a 6 month follow-up. Since driving skills may be affected by dementing disorders, as well as medications, it is anticipated that this technology will have excellent commercial viability and broad applicability for neurobehavioral research, treatment trials, and clinical assessments. PROPOSED COMMERCIAL APPLICATION: Development of a high fidelity, low cost driving simulator that is well-validated across multiple patient groups longitudinally will provide a significant tool for the assessment of "real life" functioning as it relates to driving. Potential markets include assessment of impaired drivers, monitoring of medication side effects, driver training and rehabilitation (alcohol, drugs, head injuries, disabilities, strokes, etc.), and driver education.